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Chemistry Research · @organic_chemistry
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Although the first total synthesis of taxol was accomplished nearly 30 years ago, its complex structure still motivates researchers to invent new synthetic routes. Now, Masayuki Inoue and co-workers (University of ) published a radical-based approach to the in the journal

onlinelibrary.wiley.com/doi/10

@chemistry

#orgchem #totalsynthesis #chemistry #angewandtechemie #polyketide #Japan #tokyo

Last updated 2 years ago
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Chemistry Research · @organic_chemistry
274 followers · 96 posts · Server mstdn.social

"Z-Trisubstituted α,β-Unsaturated Esters and Acid Fluorides through Stereocontrolled Catalytic Cross-Metathesis" published in by Hoveyda and co-workers (Boston College, ).
@chemistry
pubs.acs.org/doi/10.1021/jacs.

#orgchem #chemistry #USA #jacs

Last updated 2 years ago
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Chemistry Research · @organic_chemistry
274 followers · 96 posts · Server mstdn.social
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Not just a simple leaving group:
Review about recent applications of trifluoromethanesulfonic anhydride (Tf2O) written by Ning Jiao and co-workers from the East Normal University () published in .

onlinelibrary.wiley.com/doi/10

@chemistry

#orgchem #chemistry #angewandtechemie #shanghai #China

Last updated 2 years ago
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Chemistry Research · @organic_chemistry
274 followers · 96 posts · Server mstdn.social
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Can you get cyclopropanes from 1,2-diketones. You can! Chun-Xiang Zhou and co-workers from the Xiamen University () demonstrated this in the journal . A salen-type with Mo as the active metal centre mediates this reductive reaction.

A truly powerful method with the potential of follow-up work for a more general substrate scope.

pubs.acs.org/doi/10.1021/jacs.

@chemistry

#synthesis #orgchem #chemistry #catalyst #jacs #China

Last updated 2 years ago
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Chemistry Research · @organic_chemistry
274 followers · 96 posts · Server mstdn.social
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Addition of silicon nucleophiles to 3-substituted azirines:

Martin Oestreich (TU , ) and colleagues published in the catalyzed enantioselective addition of silicon nucleophiles to azirines, which the authors called cyclic strained ketimines. High yields were reported for aryl substrates, whereas non-aryl substrates gave lower yields/selectivity.

@chemistry

onlinelibrary.wiley.com/doi/fu

#orgchem #chemistry #copper #angewandtechemie #Germany #Berlin

Last updated 2 years ago
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Chemistry Research · @organic_chemistry
274 followers · 96 posts · Server mstdn.social

Synthesis of rakicidin C reported by Varinder Aggarwal and colleagues (University of , ) in the journal . Using their iterative assembly method and various coupling strategies yielding a highly convergent synthetic route.

@chemistry

pubs.acs.org/doi/10.1021/acs.o

#orgchem #chemistry #totalsynthesis #organicletters #UK #Bristol

Last updated 2 years ago
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Chemspace · @Chemspace
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#chemspace #organicchemistry #drugsynthesis #science #openscience #research #biochem #eurjoc #reagents #intermediates #chemicalbuildingblocks #fluorinecompounds #drugdiscovery #chemicals #drugdesign #medicinalchemistry #orgchem #molecule #molecularbiology #sciencefunny #laboratory #screeningcompounds

Last updated 2 years ago
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Nati Labadie (she/her) · @natilabadie
212 followers · 63 posts · Server masto.ai
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Hey everyone! Quick here: I'm Nati, a chemist finishing her PhD in Argentina. I mainly work on and but also teach at the national university of rosario. Huge nerd for everything and related, as well as and , but interested in in general.
Also a vegan acrobat shifting from one hobby to another accompanied by my kira.

#introduction #orgchem #compchem #statistics #ai #datasci #cheminformatics #rstats #python #science #cat

Last updated 2 years ago
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