Here's the latest variant picture for the new "FLip" variant DV.7.1.

The leading countries reporting DV.7.1 are Spain (9%) and Israel (4%).

DV.7.1 is from the CH.1.1.* "Orthrus" clan; DV is an alias for CH.1.1.1.1. DV.7 added the Spike L858I mutation, then DV.7.1 added the adjacent L455F and F456L mutations, hence the "FLip" nickname.

Yunlong Cao explained the advantage of this pair of mutations here:
https://twitter.com/yunlong_cao/status/1687879512237993986?s=20

HT Raj Rajnarayanan (https://twitter.com/RajlabN) for the clever "FLip" tag.

Sample volumes from many countries are now very thin and patchy, leading to some variations.

#COVID19 #FLip #DV_7_1 #CH_1_1 #Orthrus

Here's the latest variant picture for New Zealand.

XBB.1.5.* "Kraken" (28%) has rebounded to overtake CH.1.1.* "Orthrus" (25%). XBB.1.16.* "Arcturus" (16%) and XBB.1.9.* "Hyperion" (19%) are still significant.

The new EG.5.* variant (5%) is present and growing, but is not significant yet.

The vigorous mix of variants implies increased immediate reinfection risks for those relying on immunity from a prior infection. Every variant is a minority of the recent samples.

The sample volumes seem representative up to July 10.

#COVID19 #NZ #XBB_1_5 #Kraken #CH_1_1 #Orthrus #XBB_1_16 #Arcturus #XBB_1_9 #Hyperion
🧵

Here's the latest variant picture for New Zealand.

CH.1.1.* "Orthrus" (36%) rebounded to a leading position, in a close contest with XBB.1.16.* "Arcturus" (29%) and XBB.1.9.* "Hyperion" (29%).

The vigorous mix of variants implies increased immediate reinfection risks for those relying on immunity from a prior infection. Every variant is a minority of the recent samples.

The sample volumes seem representative up to June 22. Unfortunately, the update cycle for NZ seems to have fallen back to once a month. Any successful new variant will likely already be widespread by the time it appears in this data. More timely summarised frequencies are shared weekly (not via GISAID), but for a very limited set of variants.

#COVID19 #NZ #CH_1_1 #Orthrus #XBB_1_16 #Arcturus #XBB_1_9 #Hyperion
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Here's the latest variant picture for the Australian Capital Territory (ACT).

XBB.1.9.* "Hyperion" (29%) and CH.1.1.* "Orthrus" (29%) are battling for dominance.

XBB.1.16.* "Arcturus" (18%) and "Deltacron" XBC.* (13%) are still quite significant.

The chaotic mix of very different variants poses a raised immediate re-infection risk for anyone relying on natural immunity from a recent infection.

The sample volumes seem representative up to June 1.

#COVID19 #Australia #ACT #Canberra #FK_1_1 #CH_1_1 #Orthrus #XBB_1_16 #Arcturus @auscovid19

Here's the latest variant picture for Western Australia.

The XBC.* Deltacron variant clan (31%) appears to have surged to dominance, although recent samples are a bit patchy.

You could throw a blanket over XBB.1.16.* "Arcturus" (20%), XBB.1.9.* "Hyperion" (19%) and CH.1.1.* "Orthrus" (17%) variants.

XBB.1.5.* "Kraken" (9%) is still significant, along with XBB.2.3.* "Acrux" (9%).

The variant mix in WA continues to be uniquely chaotic, reflecting its situation as a global crossroads. Even WA residents who've been racking up regular reinfections are likely to meet new variants capable of overcoming their immunity. Four variants are at 17%+ frequency, with another two around 10%.

The sample volumes seem representative up to May 16.

#COVID19 #Australia #WA #Perth #XBC #Deltacron #XBB_1_9 #Hyperion #XBB_1_5 #Kraken #XBB_1_16 #Arcturus #CH_1_1 #Orthrus @auscovid19
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Here's the latest variant picture for the Australian Capital Territory (ACT).

XBB.1.9.* "Hyperion" (23%) has rebounded back to dominance.

There's been a recent surge from the last non-recombinant clan: CH.1.1.* "Orthrus" (18%).

The XBB.1.5.* "Kraken" clan (18%) is still significant.

XBB.1.16.* "Arcturus" (17%) is also quite prominent.

"Deltacron" XBC.* (16%) has been growing recently.

Be alert for conjunctivitis symptoms, particularly associated with the Arcturus variant.

The chaotic mix of very different variants poses a raised immediate re-infection risk for anyone relying on natural immunity from a recent infection.

The sample volumes seem representative up to May 17.

#COVID19 #Australia #ACT #Canberra #FK_1_1 #CH_1_1 #Orthrus #XBB_1_16 #Arcturus @auscovid19

Here's the latest variant picture for New Zealand. The sample volumes seem representative up to May 18.

XBB.1.16.* "Arcturus" (28%) has been growing steadily and now appears dominant, displacing CH.1.1.* "Orthrus" (23%).

Be alert for conjunctivitis symptoms, which seem more common with the "Arcturus" variant, although it's wave has likely peaked already by now.

XBB.1.5.* "Kraken" (19%) and XBB.1.9.* "Hyperion" (15%) are both significant.

XBB.2.3.* "Acrux" (9%) is starting to rise

The vigorous mix of variants implies increased immediate reinfection risks, for those relying on immunity from a prior infection.

#COVID19 #NZ #XBB_1_16 #Arcturus #CH_1_1 #Orthrus #XBB_2_3 #Acrux
🧵

Here's the latest variant picture for the Australian Capital Territory (ACT).

There's been an unexpected surge from the last non-recombinant clan: CH.1.1.* "Orthrus" (28%).

XBB.1.16.* "Arcturus" (24%) is also very prominent.

"Deltacron" XBC.* (18%) has been growing recently.

XBB.1.9.* "Hyperion" (14%) has falled sharply from dominance.

The XBB.1.5.* "Kraken" clan (12%) has fallen but is still significant.

The chaotic mix of very different variants poses a raised immediate re-infection risk for anyone relying on natural immunity from a recent infection.

The sample volumes seem somewhat representative up to May 12.

#COVID19 #Australia #ACT #Canberra #CH_1_1 #Orthrus #XBB_1_16 #Arcturus @auscovid19

Here's the latest SARS-CoV-2 variant picture for New Zealand:

XBB.1.5 "Kraken" (36%) became dominant in early March.

It's main rival recently has been the resurgent CH.1.1 "Orthrus" (20%). This variant is hanging on impressively in NZ - in other countries where CH.1.1 was strong, it had faded below 10% by mid-February, as XBB.1.5 took over.

Newcomer XBB.1.9.1 "Hyperion" (7%) has been rising steadily.

XBF "Bythos" has faded below 5%.

Recent sample sizes are very solid and recent, up to March 11 (see grey column chart). However the cadence of updates appears to be roughly monthly, unfortunately.

#COVID19 #NZ #XBB_1_5 #CH_1_1 #Orthrus #Kraken #XBB_1_9_1 #Hyperion #XBF #Bythos
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Here's the latest variant picture for the United Kingdom:

The XBB.1.5 "Kraken" lineage (29%) is clearly dominant now, and is still rising. There's some slower growth from CH.1.1 "Orthrus" (15%). BQ.1.1 "Cerberus" has declined (9%).

Recent samples look representative, up to 3 February.

#COVID19 #UK #CH_1_1 #Orthrus #BQ_1_1 #Cerberus #XBB_1_5 #Kraken
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Here's the latest variant picture for Singapore:

After a long lull under the XBB.1 "Hippogryph" variant, new variants are vying for dominance in Singapore, launching a new wave.

The leading candidates so far are CH.1.1.1, a child of "Orthrus" (12%), XBB.1.5 "Kraken" (11%) and XBF "Bythos" (reached 10%, possibly fading).

The fairly strong showing by XBF might help explain why XBB.1.5 has been so slow to take off in Australia, where XBF is dominant.

Recent samples look representative, up to 29 January.

#COVID19 #Singapore #CH_1_1_1 #Orthrus #XBB_1_5 #Kraken #XBF #Bythos
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CH.1.1 ‘Orthrus’: How Concerning Is This New Covid-19 Subvariant?

Guess what. Yet another new COVID subvariant has been spreading. This one’s called CH.1.1 ‘Orthrus’, and it’s a descendant of the BA.2.75. Its currently in 5th place on CDC ongoing COVID variant tracker chart in the U.S.

🇺🇸 US COVID: In the week ending February 4:

1. XBB.1.1.5 subvariant was still top dog - 66.4%
2. BQ.1.1. - 19.9%
3. BQ.1 - 7.3%
4. XBB - 2.2%
5. CH.1. 1.6%

#COVID19 #CH11 #Orthrus

Source: https://www.forbes.com/sites/brucelee/2023/02/04/ch11-orthrus-how-concerning-is-this-new-covid-19-subvariant/?sh=2b8599424bd6

''#CH11, also known as "#Orthrus" a descendent of #BA275, has been detected in over 60 countries including #NZ, #Papua New Guinea, #Cambodia and #Ireland. In the #US, 51 states have detected the new variant''

CH.1.1 (Orthrus)

"...it has the potential to be more transmissible, evade immunity from vaccine and infection, and cause more severe disease."

#Covid #Orthrus #CH11 #NewVariant #CovidIsNotOver

https://fortune.com/well/2023/01/27/meet-orthus-ch11-new-omcrion-covid-variant-delta-mutation-deltacron-convergent-evolution/

What’s CH.1.1? Meet #Orthrus, a new wildcard Omicron strain with a concerning Delta mutation https://finance.yahoo.com/news/ch-1-1-meet-orthrus-214246502.html

Here's the latest variant picture for the United Kingdom:

The XBB.1.5 "Kraken" lineage (9%) is rising rapidly, challenging the incumbents CH.1.1 "Orthrus" (20%) and BQ.1.1 "Cerebrus" (16%).

Recent samples look representative, up to 6 January.

#COVID19 #UK #CH_1_1 #Orthrus #BQ #Cerebrus #XBB_1_5 #Kraken
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Here's the latest variant picture for Hong Kong:

CH.1.1 "Orthrus" lineage (45%) appears to still be dominant, driving a wave of cases and deaths.

Recently it has been challenged by a sudden rise in the new BF.7.14 "Tarandos" lineage (36%). This is descended from the BA.5 lineage, and was first reported from China in November. I beleive this is the first significant spread of lineages out of China to other countries/territories. The sampling might not be random, e.g. targetting travellers from China.

BQ.1.1 "Cerberus" lineage (20-30%) is still present, but hasn't been dominant for some months now.

Recent samples look representative, up to 1 January.

#COVID19 #HongKong #CH_1_1 #Orthrus #BF_7_14 #Tarandos
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Orthrus Covid variant behind 1/4 of UK cases

Orthrus is the Covid variant most likely to take over from currently dominant BQ.1, which is a sub-variant of Omicron.

The #UKHSA says data suggests it could represent 100 per cent of all cases in some areas.

Areas with the highest percentage of #Orthrus variant are where a lot of people travel back & forth from India. No testing or quarantine of infected individuals traveling to UK

https://tinyurl.com/bdz253j7

#Covid19 #CovidIsNotOver

What is Orthrus? New Covid Omicron variant behind quarter of UK cases | The Independent
#CovidIsNotOver
#Covid
#CovidVariant
#Orthrus

Data suggests new variant running as high as 100% in parts of England

https://www.independent.co.uk/news/health/orthrus-covid-omicron-variant-cases-b2263689.html

Oh this just keeps getting better. It appears that the nicknaming strategy is indeed Mythical Monsters. Genius. So we have Omicron subvariants Basilisk, Minotaur, Hippogryph, the aforementioned 'Kraken', and now... Orthrus! Who? I hear you ask. Well, he's a monstrous two-headed dog, brother of the more celebrated Cerberus. Coming soon to a respiratory tract near you!

https://www.theatlantic.com/health/archive/2023/01/covid-variant-naming-xbb15-kraken/672680/

#Covid #Variants #MythicalCreatures #Orthrus