This looks like a really useful guide to how a research lab can their reduce plastic waste and carbon emissions

A case study from one department at UCL, by Bakkalci et al

https://rdcu.be/dlQRE

#PaperThemeTune: "Green" by Hiroshi Yoshimura

https://hiroshiyoshimura.bandcamp.com/album/green-sfx-version

@Cooperativity @robin_andersson Congratulations Josh & co, I look forward to reading it. I'll put my mind to a #PaperThemeTune for you. Maybe something featuring Histone-Mark E Smith...

@steveroyle what a wasted #PaperThemeTune opportunity #GoBetweens

@christlet Really beautiful work! And very useful to hear about your Review Commons experience too, thanks. Your #PaperThemeTune is "Praise You" by Fatboy SMLM

How can HDACs act as transcriptional repressors AND transcriptional activators?

Tang et al decided to find out by making various mutations in Drosophila HDAC3

They conclude that that:

* Activator activity depends on traditional catalytic activity

* But repression operates by non-enzymatic methods, including tethering loci to the nuclear periphery!

#PaperThemeTune “Hold me Back” by HDAC⚡ DC

https://journals.biologists.com/dev/article/doi/10.1242/dev.201548/323882/Separation-of-transcriptional-repressor-and

#DevBio @Dev_journal

@jamesbriscoe Congratulations Rory Daniel & @jamesbriscoe
Your #PaperThemeTune is "A Design For Life" by The Dynamical Street Preachers

@roylelab @NFerrandiz @steveroyle congratulations! May I offer you "Prove It" by Divide and Dissolve? #paperthemetune

In vetebrate embryos, the notochord induces foreplate, which then acts as an organiser to pattern the neural tube

Surprisingly, FP organisers emerge spontaneously in neural tube organoids that have no notochord

HOW ON EARTH do they do this?!

Krammer et al now tell us that
scattered FP cells undergo BMP-mediated “cluster competition’ to generate a stable ‘winning” foreplate.

A soothing #PaperThemeTune from Cluster with Brian Eno https://www.youtube.com/watch?v=nsnLPfim2Og

https://www.biorxiv.org/content/10.1101/2023.06.25.546258v1

#DevBio

Notch activation revealed to be an important stepping stone on the path to acquiring anterior-posterior identity and mesodermal fate during axis elongation.

Very interesting work from @a_tsakiridis, Fay Cooper & colleagues in Sheffield using human pluripotent cell-based models, plus some lovely chick embryo grafting data from Kim Dale's lab in Dundee

#PaperThemeTune "I'm Notch Your Stepping Stone" by the Monkees

#DevBio #StemCells #Hox #Notch #NMPs

https://www.biorxiv.org/content/10.1101/2023.06.16.545269v1

Notch activation revealed to be an important stepping stone on the path to aquiring anterior-posterior identity and mesodermal fate during axis elongation.

Very interesting work from @a_tsakiridis, Fay Cooper & colleagues in Sheffield using human pluripotent cell-based models, plus some lovely chick embryo grafting data from Kim Dale's lab in Dundee

#PaperThemeTune "I'm Notch Your Stepping Stone" by the Monkees

https://www.biorxiv.org/content/10.1101/2023.06.16.545269v1

A spoonful of Mannose helps the mesoderm go down..

Interesting work from Chaitanya Dingare, Jenny Yang, & Ben Steventon, showing that Mannose is crucial for mesoderm specification and symmetry breaking in gastruloids

https://www.biorxiv.org/content/10.1101/2023.06.05.543730v1.abstract

#PaperThemeTune from Julie Andrews. In every job that must be done, there is an element of fun! https://www.youtube.com/watch?v=_L4qauTiCY4

Just look at this beautiful paper

The Blin lab use micropatterning to measure averaged dynamic behavoirs of cell collectives in response to controlled signalling inputs.

Using this powerful approach, they reveal hidden rules behind self-organised patterning

Here, they discover how to robustly generate the elusive progenitors of the notochord

https://www.biorxiv.org/content/10.1101/2023.06.01.543323v1.article-info

#PaperThemeTune 'Notochorduroy" by The Wedding Present
https://www.youtube.com/watch?v=LccNN4ZXzJI

@cellysally you and I both know it’s the #paperThemeTune that all authors want most of all.

Really great @the_node #behindthepaper post summarising the recent discovery that epidermal cells can be co-opted to enable touch sensing. Nice work from the Tapon lab.

I enjoyed the behind-the-scenes peek into the "eureka" moment when Federica Mangione suddenly realised how 4 cells became 5 cells in the absence of any cell division...

#PaperThemeTune is of course "Touch Sensitive" by The Fall. Hey hey hey hey!

https://thenode.biologists.com/behind-the-paper-the-discovery-of-a-novel-cell-type-involved-the-fly-touch-sensing/research/

@clathrin Congratulations Steve and Mèghane! I'm not entirely sure if diffusion is the same thing as drifting, but thought you might enjoy some Jimi Hendrix for your #PaperThemeTune https://www.youtube.com/watch?v=gpw4T4ZnTlg

@scottishwaddell Congratulations! Your #PaperThemeTune comes from enGram Parsons

https://www.youtube.com/watch?v=UEDbJcIph24

Pushing the (nuclear) envelope?

Mena, usually associated with cell-surface mechanics, now found to sit in the nuclear membrane where it helps transmit mechanical information to the genome.

Seems important for nasty cancer phenotypes- I wonder, could it also help regulate much nicer developmental and homeostatic events?

https://www.nature.com/articles/s41467-023-37021-x

Congratulations @adambyron @thebyronlab Your #PaperThemeTune is Mena by Taylor Swift (who apologises for her poor spelling)

https://www.youtube.com/watch?v=jYa1eI1hpDE

@clathrin #PaperThemeTune "You Suffer" by Napalm Death #Microsong

Wow! Single cell transcriptomics reveals taste buds in the oesophagus!

https://www.science.org/doi/10.1126/sciadv.add9135

#PaperThemeTune "Taste-Buddy Holly" by Weezer
https://www.youtube.com/watch?v=Kjr7US2Z9aY

PostLights! A super-useful add-on to the already-very-useful-indeed @preLights

#PostLights provide a brief update on what has changed in a prelighted paper after the preprint has been published in a journal

Nice example here.. and it comes with a built-in #PaperThemeTune 🎶 😍

https://prelights.biologists.com/highlights/rapid-redistribution-and-extensive-binding-of-nanog-and-gata6-at-shared-regulatory-elements-underlie-specification-of-divergent-cell-fates/