#Singlechannel recordings of TRPV1 show strong coupling of permeant ion species to #ionchannel opening (completely different from other non-selective channels like AMPAR). #biophysics #patchclamp
https://www.biorxiv.org/content/10.1101/2023.05.25.542342v1?rss=1
#singlechannel #IonChannel #biophysics #patchclamp
RT @sophionbio
Great opportunity for #PhD #studentships to learn & train in one of best #ionchannel labs in the world.
With @SwissIonChannel & all beautiful #Bern, #Switzerland
#ephys #electrophysiology #patchclamp #arrythmia #cardiac #familial #genetics #channelopathies https://twitter.com/SwissIonChannel/status/1647258595774406657
#Channelopathies #genetics #familial #cardiac #arrythmia #patchclamp #electrophysiology #ephys #switzerland #bern #ionchannel #studentships #phd
New #introduction for neuromatch.social 🙂​
My group investigates and defines cell types and neural circuits of the #thalamus, #hippocampus, and #cortex that contribute to spatial #memory processes.
These processes break down in #Alzheimer's disease. To understand the causes/triggers of #neurodegeneration, we study early-stage #Tau #pathology in the human #brain and in mouse models.
I previously defined various types of retinal ganglion cells using ex vivo #patchclamp recordings during my PhD in #Basel, before moving to #Oxford to work on #GABAergic #neurons of the #hippocampus, followed by the #medialseptum. My favourite technique is in vivo #extracellular recordings and #juxtacellular labelling as it enables identification of single #cells based on their firing patterns, #axon terminal distribution, and #neurochemical profile.
As an #experimentalist, my expertise is primarily in vivo #neurophysiology and #neuroanatomy. I am also interested in #consciousness, the origins of #memory, and regulation of #neuronal activity and #behaviour by #neuropeptides.
#introduction #thalamus #hippocampus #cortex #memory #alzheimer #neurodegeneration #tau #pathology #brain #patchclamp #basel #oxford #gabaergic #neurons #medialseptum #extracellular #juxtacellular #cells #axon #neurochemical #experimentalist #neurophysiology #neuroanatomy #consciousness #neuronal #behaviour #neuropeptides
Dissertation submitted, now time to make a tantalizing PowerPoint to convince a crowd of patch clampers about the virtues of our lord and savior: multi electrode array extracellular recordings.
Any ideas about self deprecating jokes about array recordings to lower their guard in preparation for a bait and switch?
#neurosciene #thesis #patchclamp
#patchclamp #thesis #neurosciene
More hashtags
#PatchClamp #Electrophysiology #Biophysics
#biophysics #electrophysiology #patchclamp