@Alice

#Penicillin

Was der Forscher Alexander Fleming 1928 in seinen unachtsam liegen gelassenen Petrischalen entdeckt, hat die Medizin revolutioniert und ihm später einen Nobelpreis beschert. Die Entdeckung des Antibiotikums #Penicillin war ein großer Zufall.

https://www.swr.de/wissen/wie-alexander-fleming-vor-95-jahren-das-penicillin-entdeckte-100.html

Demonstration by #RCT that in patients labelled allergic to #penicillin but with low probablilty of this:
1. True allergy is actually rare
2. You can rule it out with oral penicillin challenge and not need skin testing

#IDMastodon #medicine #MedMastodon #AMR #antibiotics #allergy

https://jamanetwork.com/journals/jamainternalmedicine/fullarticle/2806976

#QuizOfTheDay: Penicillin, the first true #Antibiotic, was discovered in 1928.

Who discovered #Penicillin?

A. Alexander Fleming
B. Louis Pasteur
C. Edward Jenner
D. Robert Koch

https://knowledgezone.co.in/resources/quiz?qId=5f68a469adb45455801ab267

👉 Family to tell first #penicillin patient's story at conference

📌 The family of the first patient to be treated with penicillin hope his story will inspire pharmaceutical companies to develop new life-saving antibiotics.

📌 Albert Alexander was treated with penicillin in Oxford in 1941, demonstrating its beneficial effects.

📌His 89-year-old daughter is due to join antibiotic experts at a conference in Glasgow to tell her ancestor's story.

https://www.bbc.com/news/uk-england-berkshire-66068886?at_medium=RSS&at_campaign=KARANGA

Impactful & safe penicillin allergy delabelling.

Interesting many needed to be screened to find the low risk ones: 40 delabelled of 285 screened (14%) Worth it & not a criticism, but curious to know how long screening took #AMR #IDMastodon #MedMastodon #medicine #microbiology #antibiotics #penicillin #allergy

https://www.clinicalmicrobiologyandinfection.com/article/S1198-743X(23)00302-6/fulltext?dgcid=raven_jbs_aip_email

#IDMastodon #Cardiomastodon @ISID_org VGS species in #infectiveendocarditis patients with #Mitralvalveprolapse .In this #clinicalinvestigstion ,🔑 findings are that S. mitis represented the majority of VGS cases & despite reports of #Penicillin resistance in VGS in up to 40% of S. mitis isolates from blood cultures in patients with and without IE . No penicillin resistance was identified .
📌 https://www.sciencedirect.com/science/article/pii/S1201971223001224?dgcid=raven_sd_aip_email

Safely working out patients are not allergic to #penicillin is a big #stewardship win.

#IDMastodon #AMR #antibiotics #microbiology #MedMastodon

https://academic.oup.com/cid/advance-article-abstract/doi/10.1093/cid/ciad156/7079740#.ZBRlKH6kH6M.twitter

Die Tochter hat Streptokokken und es gibt gerade einen Mangel an #Penicillin in Europa? Nach Fiebersaft nun das? WTF? (Sie hat nun ein breiter angesetztes #Antibiotikum bekommen. Immerhin, aber natürlich nicht optimal.)

The fight against antibiotic resistance is growing more urgent, but artificial intelligence can help
#AI #ArtificalIntelligence #Bacteria #Antibiotics #Algorithms #AntibioticResistance #DrugDiscovery #Penicillin #AntibioticResistantBacteria
https://the-14.com/the-fight-against-antibiotic-resistance-is-growing-more-urgent-but-artificial-intelligence-can-help/

An argument is made that penicillin is the reason the allies won world was two.

https://youtu.be/QeSMbTrn4Gc

#History #Medicine #War #Antibiotics #Penicillin #WorldWar2 #Fungi #Disease #STDs #Infection #Science #Culture #Discovery #Industry #Defense #MilitaryIndustrialComplex

The trick, of course, is to not decimate the library while searching for a single best seller. Humans have a bad track record of that going back millennia. (See #Silphium.)
2/2

https://en.m.wikipedia.org/wiki/Silphium

#Medicine #NaturalMedicine #WhereMedicineComesFrom #Penicillin #Digitalis #Tamoxifen #Aspirin

Hurra, wir haben EINE !!1! Packung #Penicillin aus der Vorbestellung vom Großhandel erhalten und warten jetzt auf den glücklichen Gewinner, der als erstes mit einem #Rezept vorbeikommt, falls überhaupt noch einen Arzty hoffnungsvoll Penicillin aufschreibt 😇

@TimChp

Hmmm... was that an Assam?

(Nice teapot BTW)
#science #tea #penicillin

Ok, yes, I'm a bit embarrassed to open the lid publicly on this recent kitchen find, but on the other hand mastodonians are all such kindly nonjudgmental people and it's also a pretty fascinating #FungiFriday picture and best of all I do think I've totally discovered the real reason why tea is good for you.

#science #tea #penicillin

Interesting exploration of the diverse impacts of beta lactam #antibiotics including #penicillin on Escherichia coli that suggest these antibiotics can self-promote entry through the outer cell membrane.

New research in Nature Communications on:

https://www.nature.com/articles/s41467-022-35528-3

#microbiology #bacteria

The UK *at last* declares 'serious shortage protocols' for specific #penicillin medicines - which will allow #pharmacists to prescribe alternative formulations of the #antibiotics - after the significant rise in cases of Group A #Streptococcus. #StrepA

https://www.gov.uk/government/news/update-on-alternative-penicillin-protocols-for-pharmacists

#StrepA: Five more ‘serious shortage protocols’ issued for #penicillin as cases surge https://www.independent.co.uk/news/health/antibiotic-shortages-penicillin-strep-cases-b2247114.html

#StrepA: Five more ‘serious shortage protocols’ issued for #penicillin as cases surge https://www.independent.co.uk/news/health/antibiotic-shortages-penicillin-strep-cases-b2247114.html

LONDON - The UK government on Thursday admitted there were serious shortages of #antibiotics to treat bacterial infections in children, despite more than a week of denials.

“Serious shortage protocols” had been issued for three types of oral solutions used in paediatrics – #Phenoxymethylpenicillin, which is also known as #penicillin V.

https://www.straitstimes.com/world/europe/uk-govt-admits-antibiotic-shortage