New #PalliativeCare adjacent question. I traditionally with opioids start low and titrate up based on response. Has anyone ever seen practice of using weight +\- age to estimate the initial starting dose say of oral morphine? Seen recently (not in palliative care) and was a bit suprised
#Palliativemedicine #HAPC #analgesia #morphine #pharmacokinetic

Rare but serious reports of liver damage from #turmeric ingestion are increasing. It may be driven by improvements to the #pharmacokinetic profile by the addition of black pepper which appears to inhibit #glucuronidation. Harms seem to be more likely among those with a specific genetic trait. https://sciencebasedmedicine.org/liver-damage-associate-with-turmeric-ingestion/