Structure of #tau #CTE filaments with @LillyPad PET tracer #flortaucipir. A surprising find, as this compound is used in the clinic for #AD, but we could not see #cryoEM density for the compound on tau #PHFs or #SFs. With @sy31802 & @MichelGoed.
https://www.biorxiv.org/content/10.1101/2022.12.15.520545v1
#tau #cte #flortaucipir #ad #CryoEM #phfs #SFS