I am also looking to hire a post-doc to perform in vivo #photopharmacology to study the physiological role of specific NMDA receptor subtypes. So, if you are interested in this subject, have experience in behavior or in vivo optogenetics, and are at #NeuroFrance2023 please send me your poster number and I will try to come see you.
#photopharmacology #neurofrance2023
I will have a talk at #NeuroFrance2023 during the S24 session (Thursday May 25th 15:30). If you are interested in #photopharmacology and #glutamate receptors, please come listen to my talk and the other great talks of this session.
#neurofrance2023 #photopharmacology #glutamate
“To expand the repertoire of endogenous cellular communication, we developed a synthetic, photon-assisted synaptic transmission (PhAST) system. PhAST is based on luciferases and channelrhodopsins that enable the transmission of a neuronal state across space, using photons as neurotransmitters.”
Porta-de-la-Riva et al. 2023 https://www.nature.com/articles/s41592-023-01836-9
What a fun project and cool finding, and made in #Catalunya to top it off at the Photonic Science Institute.
Combine that with #photopharmacology and neural circuits may be able to dose themselves according to activity patterns.
#neuroscience #PhAST #Luciferase #ChannelRhodopsin #biophotonics #optogenetics
#optogenetics #biophotonics #channelrhodopsin #luciferase #phast #neuroscience #photopharmacology #catalunya
In vivo #photopharmacology with a caged mu #opioid receptor agonist drives rapid changes in #behavior
#pain #neuroscience #syntheticbiology
https://doi.org/10.1038/s41592-023-01819-w
#photopharmacology #opioid #behavior #pain #neuroscience #syntheticbiology
Bioactive #aurones, #indanones, and other #hemiindigoid #scaffolds: #Medicinal #chemistry and #photopharmacology Perspectives https://dx.doi.org/10.1021/acs.jmedchem.2c01150 #IMBEpapers #inhibition #inhibitors #peptides #proteins #reaction products #selectivity
#aurones #indanones #hemiindigoid #scaffolds #medicinal #chemistry #photopharmacology #imbepapers #inhibition #inhibitors #peptides #proteins #reaction #selectivity
Bioactive #aurones, #indanones, and other #hemiindigoid #scaffolds: #Medicinal #chemistry and #photopharmacology Perspectives https://dx.doi.org/10.1021/acs.jmedchem.2c01150
#aurones #indanones #hemiindigoid #scaffolds #medicinal #chemistry #photopharmacology