The EMBO Journal · @embojournal
525 followers · 260 posts · Server sciencemastodon.com
Extra #centrosomes are initially anti-#tumorigenic but why?
Irmina Garcia-Carpio, Andreas Villunger et al find that through #PIDDosome activation, they not only induce #p53 responses, but also #NFkB signaling to increase #immunogenicity of cancer cells
https://www.embopress.org/doi/full/10.15252/embj.2023113510
#centrosomes #tumorigenic #piddosome #P53 #nfkb #immunogenicity
Last updated 1 year ago