@medrxivpreprint
The commonly used #antibiotics #amoxicillin, #metronidazole, #piperacillin-tazobactam & #Clindamycin reached levels equivalent to blood within infected pleural fluid.Low penetration of trimethoprim into the pleural space raised concerns about the use of #cotrimoxazole for patients with #Pleuralinfection or parapneumonic effusions.
#Antibiotic #pharmacokinetics in infected #pleuraleffusions
https://www.medrxiv.org/content/10.1101/2023.09.08.23295282v1.full.pdf
#antibiotics #Amoxicillin #metronidazole #piperacillin #clindamycin #cotrimoxazole #pleuralinfection #antibiotic #pharmacokinetics #pleuraleffusions