'The extrinsic incubation period (EIP), defined as the time it takes for malaria parasites in a mosquito to become infectious to a vertebrate host, is one of the most influential parameters for malaria transmission but remains poorly understood.'

#Preprint #Malaria #Plasmodium

https://www.biorxiv.org/content/10.1101/2023.08.22.554268v1

Pour la première fois depuis 20 ans, 8 cas autochtones de #paludisme à #Plasmodium vivax ont été détectés en 2023 aux USA 🇺🇸 : 7 en Floride et 1 au Texas.

https://www.vox.com/science/2023/6/23/23771154/malaria-transmission-florida-texas-mosquitoes-risk-prevention-anopheles

Cette réémergence du paludisme serait-elle possible en France 🇫🇷 ?
Aucune transmission autochtone de paludisme n’a été observée en France Métropolitaine depuis les années 1972… A l’exception d’un cas autochtone de paludisme à Plasmodium vivax en Corse en 2006. 1/n

Florida malaria outbreak still going with local cases now at 7 - An Anopheles stephensi mosquito, which can carry the malaria parasite. ... - https://arstechnica.com/?p=1955210 #infectiousdisease #plasmodiumvivax #publichealth #mosquitoes #plasmodium #outbreak #sarasota #science #florida #malaria #health

Ars Technica: Florida malaria outbreak still going with local cases now at 7 https://arstechnica.com/?p=1955210 #Tech #arstechnica #IT #Technology #Infectiousdisease #plasmodiumvivax #publichealth #mosquitoes #Plasmodium #outbreak #sarasota #Science #Florida #malaria #Health

@cyrilpedia
Now that is super cool #science!!!
@odomjohnlab

#malaria #plasmodium

Malaria on a chip.

'A functional, multi-organ, serum-free system was developed for the culture of P. falciparum in an attempt to establish innovative platforms for therapeutic drug development. It contains 4 human organ constructs including hepatocytes, splenocytes, endothelial cells, as well as recirculating red blood cells which allow for infection with the parasite. '

#Malaria #Plasmodium

https://www.nature.com/articles/s41598-023-35694-4

#Malaria in Florida, What is #Plasmodium vivax?

📌 7 locally transmitted malaria cases have been reported in the US (Texas and Florida), a first in quite a few years.

📌 The species of malaria has been identified as Plasmodium vivax, one of 5 plasmodium species that can infect humans.

http://outbreaknewstoday.com/malaria-in-florida-what-is-plasmodium-vivax-66835/

Five cases of locally acquired #malaria ( #Plasmodium vivax) in the 🇺🇸 (TX & FL). These are the first such cases recorded in 20 years.

Quote: “…a changing #climate and shifting weather patterns increasingly drive #mosquito migration into new places worldwide, allowing malaria to settle in where it hasn’t before.”

🦟 🦟🦟🦟🦟

🔗 https://www.vox.com/science/2023/6/23/23771154/malaria-transmission-florida-texas-mosquitoes-risk-prevention-anopheles

#ClimateChange #PublicHealth

Malaria spreading in Texas and Florida; first US-based cases in two decades - Enlarge

The Centers for Disease Control and Prevention is war... - https://arstechnica.com/?p=1950308 #plasmodium #outbreak #science #florida #malaria #p.vivax #health #texas #cdc

Ars Technica: Malaria spreading in Texas and Florida; first US-based cases in two decades https://arstechnica.com/?p=1950308 #Tech #arstechnica #IT #Technology #Plasmodium #outbreak #Science #Florida #malaria #P.vivax #Health #texas #CDC

New research article in The Lancet Infectious Diseases>

#Ganaplacide (KAF156) plus #lumefantrine solid dispersion formulation combination for uncomplicated #Plasmodium #falciparum #malaria: an open-label, multicentre, parallel-group, randomised, controlled, phase 2 trial

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(23)00209-8/fulltext

New research article in The Lancet Microbe>

Association between domesticated animal ownership and #Plasmodium #falciparum parasite prevalence in the Democratic Republic of the Congo: a national cross-sectional study

https://www.thelancet.com/journals/lanmic/article/PIIS2666-5247(23)00109-X/fulltext

#malaria

P. falciparum adapts investment to replication vs transmission according to host environment. Our latest Marti lab article https://t.co/hTLUiGSxXT @eLife #malaria #plasmodium #plasmodiumfalciparum #elife

New research sheds light on how #malaria parasites #adapt to their human hosts.

#evolution #arms_race #Plasmodium #lysophospatidylcholin

https://phys.org/news/2023-03-malaria-parasites-human-hosts.html

RT @RoliRoberts
First talk at #EESSymbiosis - @MariaMMota2 talking about #Plasmodium's quiet life in the liver, and how it can induce a protective effect (via γδT cells) against later blood-stage disease.

My first preprint in Canada 🇨🇦 from the wonderful Wasmuth lab. My first preprint in a new field - parasitology!

We used protein structures to identify molecular mimicry in Plasmodium falciparum.

https://www.biorxiv.org/content/10.1101/2023.02.08.527763v1?rss=1

#parasitology #malaria #plasmodium #preprint #canada #parasites #bioinformatics

"Depleting nutrients by dilution of culture medium caused parasites to produce less merozoites and reduced proliferation but did not affect cell volume or total nuclear volume at the end of schizogony. Our findings suggest that malaria parasites use a resource-dependent counter mechanism to optimize their progeny number during blood stage infection."

#Preprint #Malaria #Plasmodium

https://www.biorxiv.org/content/10.1101/2023.01.20.524890v1?med=mas

On the worsening #AntiMalarial #DrugResistance in #Africa

#malaria #drugs #artemisinin #PlasmodiumFalciparum #Plasmodium #falciparum #protozoa #Anopheles #mosquito

https://www.dw.com/en/africa-antimalarial-drug-resistance-on-the-rise/a-64306141

'In #malaria parasites, sexual reproduction coincides with transmission to the vector host. Sex determination is non-genetic, with each haploid parasite capable of producing either a male or a female gametocyte in the human host. The hierarchy of events and molecular mechanisms that trigger sex determination and maintenance of sexual identity are yet to be elucidated.'
#Plasmodium

https://www.nature.com/articles/s41586-022-05509-z

When the #plasmodium/#malaria people get in here... hi y'all! 👋