In the paper we managed for the first time to combine #connectomics, calcium #imaging from all neurons of a fully-mapped circuit, genetic perturbations, behaviour and computational modelling. #Platynereis for systems #neuroscience

We published a new preprint on nitric oxide (NO) signalling in #Platynereis. In the paper Kei Jokura et al. described how NO is required for UV-avoidance behaviour by mediating retrograde signalling to brain ciliary photoreceptors.
https://www.biorxiv.org/content/10.1101/2023.08.02.551600v1
#neuroscience #animals #science

Our favourite #Platynereis #opsin now in the mammalian brain as a new #optogenetic tool!

"Here we ... found that the Platynereis dumerilii ciliary opsin ... is an efficient, versatile, light-activated bistable GPCR that can suppress synaptic transmission in mammalian neurons with high temporal precision in-vivo "

https://www.biorxiv.org/content/10.1101/2023.07.01.547328v1

#neuroscience #GPCR

ICB’s Tuesday Blog-
#Lunar lessons from #Platynereis: what can marine #worms teach us about our relationship with the moon?

by Joseph Mack about Dr. Kristin Tessmar-Raible of @MaxPerutzLabs

https://integrativeandcomparativebiology.wordpress.com/2023/03/07/lunar-lessons-from-platynereis-what-can-marine-worms-teach-us-about-our-relationship-with-the-moon/

#invertebrate #biology #WomeninScience #WomenInSTEM #moon

RT @COSHeidelberg
We are happy to welcome Gaspar Jekely (@JekelyLab) as full professor at COS focusing on evolutionary neurobiology mostly using #Platynereis larvea as an experimental system. A new and exciting research line @UniHeidelberg !

RT @stemdevevo@twitter.com

or #platynereis posterior regeneration --> https://www.sciencedirect.com/science/article/pii/S0012160618304536?via%3Dihub

🐦🔗: https://twitter.com/stemdevevo/status/1485267730941026305

RT @stemdevevo@twitter.com

If you want to know more about #platynereis posterior growth --> https://www.sciencedirect.com/science/article/pii/S0012160613003813?via%3Dihub

🐦🔗: https://twitter.com/stemdevevo/status/1485267650695548928

RT @stemdevevo@twitter.com

Our results are therefore consistent with a key role of brain hormonal activity in the control of regeneration and growth in #platynereis, and support the hypothesis of the involvement of methylfarnesoate in this control.

🐦🔗: https://twitter.com/stemdevevo/status/1485267402803843080

RT @stemdevevo@twitter.com

In #Platynereis juvenile worms, the ability to grow posteriorly and to regenerate their posterior part is promoted by a brain hormone. When this hormonal activity becomes low, the worms undergo sexual maturation, and this ability to regenerate and grow posteriorly stops.

🐦🔗: https://twitter.com/stemdevevo/status/1485266015260979202

RT @stemdevevo@twitter.com

Our last paper is now on @biorxivpreprint@twitter.com! In this study led by our former post-doc @PatrialvarezCam@twitter.com, with the help of @AnaPlanques@twitter.com, and L. Bideau, we analyze the hormonal control of posterior regeneration and growth in #Platynereis @IJMonod@twitter.com @INSB_CNRS@twitter.com
https://www.biorxiv.org/content/10.1101/2022.01.21.477205v1

🐦🔗: https://twitter.com/stemdevevo/status/1485263733454782467