PRS eli #polygeeninenriskisumma (#polygenicriskscore #prs), joka kertoo paljonko tietylle taudille altistavia perintötekijöitä kullakin on, hävisi vertailun sepelvaltimoiden kalkin määrälle kysyttäessä kumpi tuo perinteisten riskitekijöiden päälle vielä lisäarvoa kun kyseessä #sepelvaltimotautiriski.
#genetiikka

https://jamanetwork.com/journals/jama/fullarticle/2805138
#jama

#JustOneFigure from a recently published paper: the association of a polygenic risk score for (continuous) sleep duration with cognitive outcomes. Higher values of the PRS have protective association against mild cognitive impairment (MCI) in individuals who are categorized as “short” and “normal” sleepers, but is associated with increased MCI risk in individuals categorized as “Long sleepers” — self reported to sleep more than 9 hours a night. #PolygenicRiskScore #Sleep #CognitiveAging