Gezocht door collega’s in Amsterdam: postdoctoraal onderzoeker die meehelpt de Ziekte van #Huntington te onderzoeken. Meer info hier: https://werkenbij.amsterdamumc.org/en/vacatures/research/postdoc-huntington-and-ataxia-
#polyQ #ziektevanhuntington #onderzoek #biochemie #neuroscience
#huntington #polyq #ziektevanhuntington #onderzoek #biochemie #neuroscience
Drosophila melanogaster as a model to study autophagy in neurodegenerative diseases induced by proteinopathies https://pubmed.ncbi.nlm.nih.gov/37274187/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230612113147&v=2.17.9.post6+86293ac by Paola Bellosta #polyQ #review #article
Mitochondrial dysfunction and oxidative stress in Alzheimer's disease, and Parkinson's disease, Huntington's disease and Amyotrophic Lateral Sclerosis -An updated review https://pubmed.ncbi.nlm.nih.gov/37269968/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230612113147&v=2.17.9.post6+86293ac by Arabinda Ghosh #polyQ #review #article
Therapeutic Strategies for Spinocerebellar Ataxia Type 1 https://pubmed.ncbi.nlm.nih.gov/37238658/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230612113147&v=2.17.9.post6+86293ac by Ronald A M Buijsen #polyQ #review #article
The structural plasticity of polyglutamine repeats https://pubmed.ncbi.nlm.nih.gov/37178477/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230612113147&v=2.17.9.post6+86293ac by Sandra Macedo-Ribeiro #polyQ #review #article
Autophagy in Spinocerebellar Ataxia Type 3: From Pathogenesis to Therapeutics https://pubmed.ncbi.nlm.nih.gov/37108570/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230612113147&v=2.17.9.post6+86293ac by Clévio Nóbrega #polyQ #review #article
Contribution of Glial Cells to Polyglutamine Diseases: Observations from Patients and Mouse Models https://pubmed.ncbi.nlm.nih.gov/37020152/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230406100400&v=2.17.9.post6+86293ac by Michelle Gray #polyQ #review #article
Advances in Nucleotide Repeat Expansion Diseases: Transcription Gets in Phase https://pubmed.ncbi.nlm.nih.gov/36980167/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230403035802&v=2.17.9.post6+86293ac by Isabel Silveira #polyQ #review #article
Ubiquitin-modifying enzymes in Huntington's disease https://pubmed.ncbi.nlm.nih.gov/36926679/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230317161526&v=2.17.9.post6+86293ac by Eric A Reits #polyQ #review #article
The potential of gene editing for Huntington's disease https://pubmed.ncbi.nlm.nih.gov/36907678/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230313040644&v=2.17.9.post6+86293ac by Mark P Mattson #polyQ #review #article
What the Gut Tells the Brain-Is There a Link between Microbiota and Huntington's Disease? https://pubmed.ncbi.nlm.nih.gov/36901907/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230311155151&v=2.17.9.post6+86293ac by Lukasz Przybyl #polyQ #review #article
Astrocytic contributions to Huntington's disease pathophysiology https://pubmed.ncbi.nlm.nih.gov/36864567/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230303081442&v=2.17.9.post6+86293ac by Steven A Goldman #polyQ #review #article
Myelinating Glia: Potential Therapeutic Targets in Polyglutamine Spinocerebellar Ataxias https://pubmed.ncbi.nlm.nih.gov/36831268/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230228144446&v=2.17.9.post6+86293ac by Hayley S McLoughlin #polyQ #review #article
The Homogeneous Azorean Machado-Joseph Disease Cohort: Characterization and Contributions to Advances in Research https://pubmed.ncbi.nlm.nih.gov/36830784/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230228144446&v=2.17.9.post6+86293ac by João Vasconcelos #polyQ #review #article
The role of PQBP1 in neural development and function https://pubmed.ncbi.nlm.nih.gov/36815699/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230228144446&v=2.17.9.post6+86293ac by Junhai Han #polyQ #review #article
Subtyping monogenic disorders: Huntington disease https://pubmed.ncbi.nlm.nih.gov/36803810/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230228144446&v=2.17.9.post6+86293ac by Alberto J Espay #polyQ #review #article
Atrophin-1 Function and Dysfunction in Dentatorubral-Pallidoluysian Atrophy https://pubmed.ncbi.nlm.nih.gov/36809552/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230223042554&v=2.17.9.post6+86293ac by Agnieszka Fiszer #polyQ #review #article
Excited to again attend the annual Dutch Huntington research meeting, Monday next week! I guess this is sort of the 2022 version in early 2023 :) Hosted at uniQure in Amsterdam, with many interesting speakers and posters. Come to hear about our ongoing work on figuring out how #polyQ proteins misfold and aggregate, and how we try to prevent and change that bad protein behavior. We are looking forward to see you there! #huntingtondisease #amyloid
More info: http://huntingtonresearch.nl
#polyq #huntingtondisease #amyloid
The evolution and polymorphism of mono-amino acid repeats in androgen receptor and their regulatory role in health and disease https://pubmed.ncbi.nlm.nih.gov/36388907/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1bk4uPJPP8lmd7AdzeQel2i2S7InXyQTk_e5qal8pFmKtFIM1K&fc=20230115145415&ff=20230115145512&v=2.17.9.post6+86293ac by Tamas Lazar #polyQ #review #article
Mushroom Natural Products in Neurodegenerative Disease Drug Discovery https://pubmed.ncbi.nlm.nih.gov/36497196/?utm_source=Other&utm_medium=rss&utm_campaign=pubmed-2&utm_content=1HSIVAEu7c8847SqiZFqTN51FhK9TwS7kVQm_o8CvDdy-ENMA0&fc=20230114165135&ff=20230114170507&v=2.17.9.post6+86293ac by Joe Tiralongo #polyQ #review #article