The EMBO Journal · @embojournal
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How do #botulinum toxins get to nerve ends to mediate #neurointoxication?
F. Meunier Lab shows that BoNT/A uptake into #synaptic #vesicles is via hijacking of a tripartite membrane nanocluster of #polysialogangliosides, #synaptotagmin and glycoprotein SV2
https://www.embopress.org/doi/10.15252/embj.2022112095
#botulinum #neurointoxication #synaptic #Vesicles #polysialogangliosides #synaptotagmin
Last updated 1 year ago