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Alan Kotok · @technewslit
1057 followers · 591 posts · Server journa.host

Researchers use stem cells to generate human neurons resembling those in the brain that control breathing during opioid reactions, for eventual chip devices to test overdose therapies.

sciencebusiness.technewslit.co

#News #press #science #business #opioid #overdose #preclinical #toxicity #neurons #breathing #naloxone #fentanyl #codeine #brain #methadone #stemcells #biotechnology #engineering #chemistry

Last updated 1 year ago
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Alan Kotok · @technewslit
1030 followers · 551 posts · Server journa.host

A women's health biotechnology company is partnering with a Brazilian drug maker to evaluate a precision target and treatment for ovarian health disorders.

sciencebusiness.technewslit.co

#News #press #science #business #biotechnology #collaboration #melatonin #womenshealth #ovaries #pcos #precisionmedicine #infertility #brazil #preclinical #licensing

Last updated 1 year ago
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Alan Kotok · @technewslit
1011 followers · 523 posts · Server journa.host

A group of academic and industry researchers exhibited in lab cells and mice a more direct delivery technique that could make gene therapies more accessible and inexpensive.

sciencebusiness.technewslit.co

#News #press #science #business #biotechnology #genetics #genetherapy #lipidnanoparticles #mRNA #sicklecell #stemcells #preclinical #bonemarrow

Last updated 1 year ago
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Alan Kotok · @technewslit
999 followers · 519 posts · Server journa.host

A biotechnology company creating living tissue from a person's stem cells says it received FDA clearance for a clinical trial of its replacement knee cartilage.

sciencebusiness.technewslit.co

#News #press #science #business #tissue #engineering #regenerativemedicine #stemcells #ClinicalTrial #bone #cartilage #biotechnology #preclinical #bonemarrow #adipose #university

Last updated 1 year ago
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Alan Kotok · @technewslit
948 followers · 471 posts · Server journa.host
Open media

Biochip Device Tests Malaria Drug Efficacy, Safety

A lab-on-a-chip device with human organ cells is shown in lab tests to distinguish between malaria strains and detect drug toxicity when assessing blood for seven days.

sciencebusiness.technewslit.co

#News #science #business #malaria #parasite #biochip #MedicalDevice #preclinical #engineering #microfluidic #blood #toxicity #liver #spleen

Last updated 1 year ago
Original post

Giuseppe Michieli · @GMIK69
68 followers · 1447 posts · Server mstdn.science

Vectored and of -CoV-2 infection in a model, PNAS: doi.org/10.1073/pnas.230350912

#immunoprophylaxis #Treatment #sars #preclinical

Last updated 1 year ago
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Alan Kotok · @technewslit
852 followers · 383 posts · Server journa.host
Open media

Safer Forms of Psilocybin Assessed in Preclinical Study

A company says it identified engineered precursors of a compound that in lab produce safe and intended therapeutic effects.

sciencebusiness.technewslit.co

#biotechnology #psychedelic #animals #News #science #business #psilocybin #magicmushrooms #chemistry #canada #mentalhealth #psychoactive #preclinical #prodrug

Last updated 2 years ago
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Alan Kotok · @technewslit
825 followers · 361 posts · Server journa.host
Open media

Crispr Therapy Shown to Remove E. Coli in Gut

New with lab shows gene-edited viruses can target and remove harmful E. coli from the , including strains usually resistant to .

sciencebusiness.technewslit.co

#research #animals #bacteria #gut #antibiotics #News #science #business #biotechnology #genomics #geneediting #crispr #ecoli #preclinical #microbiome #antibioticresistance #gutmicrobes

Last updated 2 years ago
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Alan Kotok · @technewslit
802 followers · 345 posts · Server journa.host
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Low-Dose Covid-19 Vaccine Generates Strong Immune Response

Ultra-low quantities of an experimental Covid-19 delivered in synthetic cell components are shown in lab animals to generate strong responses.

sciencebusiness.technewslit.co

#protein #vaccine #immune #News #science #business #biotechnology #COVID19 #SarsCoV2 #preclinical #exosomes #nanoscale #immuneresponse #antibody #Tcells

Last updated 2 years ago
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Knight ADRC · @KnightADRC
54 followers · 533 posts · Server universeodon.com
Open media

New paper alert in Neurology: Here, @Pamlukasewicz showed that changes in plasma p-tau181 and NfL have the potential to be used as surrogate biomarkers in large scale clinical trials targeting . n.neurology.org/content/early/

#preclinical #alzheimerdisease

Last updated 2 years ago
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Alan Kotok · @technewslit
751 followers · 277 posts · Server journa.host
Open media

Industry, Academic Labs Detailing ALS Treatment Actions

Researchers from a developer of disease and medical center are investigating the precise workings of a promising treatment.

sciencebusiness.technewslit.co

#neurodegenerative #therapies #university #als #News #science #business #biotechnology #collaboration #neuroscience #neurons #preclinical #clinicaltrials #laboratory #brain #nervoussystem

Last updated 2 years ago
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Malcolm Macleod · @malcolm_macleod
62 followers · 108 posts · Server nerdculture.de
Open media

RT @preclinicaldata
.GoEQIPD is hosting a webinar series discussing how researchers and stakeholders can enhance the quality of preclinical data. The next is "Exploratory versus confirmatory research" with Dr. René Bernard from @questbih on March 29. go-eqipd.org/about-eqipd/webin

#preclinical #research

Last updated 2 years ago
Original post

Alan Kotok · @technewslit
735 followers · 244 posts · Server journa.host
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Gene Therapy Shown to Build Knee Cartilage

Findings from with lab shows a single injection delivered with a benign virus helps build new cells and tissue.

sciencebusiness.technewslit.co

#research #animals #gene #therapy #knee #cartilage #News #science #business #arthritis #osteoarthritis #genetherapy #pain #proteins #collaboration #preclinical #biotechnology #inflammation

Last updated 2 years ago
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Alan Kotok · @technewslit
723 followers · 229 posts · Server journa.host
Open media

Business-Academic Team to Create RNA Delivery for Cancer

A lab and company are developing new treatments with therapies that stop activity, delivered by advanced particles.

sciencebusiness.technewslit.co

#university #biotechnology #cancer #RNA #nanoscale #News #science #business #chemistry #collaboration #licensing #pharmacology #pancreaticcancer #preclinical #mirna #silicon #uk #germany

Last updated 2 years ago
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Alan Kotok · @technewslit
720 followers · 225 posts · Server journa.host
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mRNA Aerosol Delivered to Lungs to Treat Pneumonia

Messenger , inhaled from an , is shown in lab rats with to reduce , improve functions, and protect against further .

sciencebusiness.technewslit.co

#RNA #Aerosol #spray #pneumonia #inflammation #lung #infections #News #science #business #collaboration #mRNA #nucleicacid #ARDS #preclinical #biotechnology #chemistry #nanotechnology #ireland

Last updated 2 years ago
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Alan Kotok · @technewslit
697 followers · 202 posts · Server journa.host
Open media

Biotech Drug Shown to Kill Prostate Tumor Cells

Tests with lab mice show low doses of an experimental oral can selectively kill cells while not affecting surrounding healthy tissue.

sciencebusiness.technewslit.co

#drug #prostate #cancer #News #science #business #ProstateCancer #tumor #preclinical #biotechnology #chemistry #biochemistry #oncology #proteins #university #Entrepreneurs

Last updated 2 years ago
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PLOS Biology · @PLOSBiology
4673 followers · 772 posts · Server fediscience.org
Open media

RT @Team_Blueprint
Excited to share our recent publication in @PLOSBiology! This interview study gives us insight into the barriers and enablers of rigorous conduct and reporting in laboratory studies! tinyurl.com/plosb (1/8)

#preclinical

Last updated 2 years ago
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Alan Kotok · @technewslit
676 followers · 170 posts · Server journa.host
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Implanted Tissue Shown to Produce Thyroid Hormones

In a test, tissue earlier removed from lab animals was re-implanted in a protective pouch, which generates production of key by the animals.

sciencebusiness.technewslit.co

#preclinical #Thyroid #hormones #News #science #business #implant #surgery #biotechnology #regenerativemedicine #chronicdisease #endocrine #canada #university

Last updated 2 years ago
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Thiago Carvalho · @cyrilpedia
1487 followers · 4133 posts · Server qoto.org

"Here, we present data on preclinical studies in mice of a receptor-binding domain (RBD)-based recombinant protein vaccine candidate (PHH-1V) consisting of an RBD fusion heterodimer comprising the B.1.351 and B.1.1.7 SARS-CoV-2 VoCs formulated in SQBA adjuvant, an oil-in-water emulsion."

biorxiv.org/content/10.1101/20

#preprint #SarsCoV2 #preclinical #vaccine

Last updated 2 years ago
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Alan Kotok · @technewslit
661 followers · 145 posts · Server journa.host
Open media

Nasal Spray Vaccine Shown to Stop Gonorrhea Infections

A against given as a nasal spray is shown to generate protective responses in lab mice of both sexes, and in females similar to an intravaginal vaccine.

sciencebusiness.technewslit.co

#vaccine #gonorrhea #immune #News #science #business #NasalSpray #std #bacteria #gramnegative #preclinical #biotechnology #chemistry #cytokines #Formulation #collaboration

Last updated 2 years ago
Original post