LBNL BioSci · @LBNLBioSci
103 followers · 160 posts · Server sciencemastodon.com

Using X-ray crystallography at the Advanced Light Source (ALS), research scientist Banumathi Sankaran at the Berkeley Center for Structural Biology (BCSB) has helped confirm the successful design of proteins that toggle between two different shapes in response to biological triggers.

Read more: biosciences.lbl.gov/2023/08/29

Berkeley Lab

#proteindesign #MachineLearning #structuralbiology #science #RoseTTAFold #proteinmpnn #AlphaFold2

Last updated 1 year ago

Phys.org · @physorg_bot
461 followers · 11911 posts · Server social.platypush.tech
Phil Leung · @proleu
22 followers · 14 posts · Server mastodon.cloud
Folmer · @folfdk
226 followers · 771 posts · Server mastodon.social
michael · @proseandpassion
343 followers · 1649 posts · Server mastodon.social
Dave Briggs :protein: · @xtaldave
1201 followers · 3954 posts · Server xtaldave.net

Large language models generate functional protein sequences across diverse families.

Super interesting work.

@strucbio
nature.com/articles/s41587-022

#proteindesign #structuralbiology #crystallography

Last updated 2 years ago

Aging Highlights · @senescence
233 followers · 133 posts · Server mas.to
Cyrus Biotechnology · @official
16 followers · 13 posts · Server social.cyrusbio.com

@sokrypton Congrats all! Very exciting to push this combination of language models and structure models. AF2 and OF have been frustrating for design, not too surprisingly, but this all makes a ton of sense as a next step!

#drugdiscovery #ai #proteinai #proteindesign

Last updated 2 years ago

Cyrus Biotechnology · @official
3 followers · 8 posts · Server social.cyrusbio.com

7/
Cyrus also recently co-founded the OpenFold consortium for biological AI with Prescient/Genentech, Arzeda, Outpace and help from AWS, to help provide fully open sourced platform models in molecular modeling (openfold.io).

Learn more here:
Cyrusbio.com

#ai #drugdiscovery #proteinai #proteindesign #structbio

Last updated 2 years ago

Dave Briggs :protein: · @xtaldave
1103 followers · 2682 posts · Server xtaldave.net

This feels very futuristic.

A de novo protein catalyzes the synthesis of semiconductor quantum dots
pnas.org/doi/abs/10.1073/pnas.

@strucbio

#structuralbiology #proteindesign #Science

Last updated 2 years ago

Folmer · @folfdk
147 followers · 296 posts · Server mastodon.social

David Bakers talk
"The coming of age of de novo protein design" at the NIH from Dec. 14th

@strucbio

videocast.nih.gov/watch=46050

#proteindesign #enzymeengineering

Last updated 2 years ago

Aging Highlights · @senescence
202 followers · 90 posts · Server mas.to

De novo protein design by inversion of the AlphaFold structure prediction network

biorxiv.org/content/10.1101/20

#alphafold #proteindesign #preprint

Last updated 2 years ago

Dec 13th at 12pm EST
Join to learn about Proteus, a general purpose tool for protein design, used to redesign entire proteins or functional sites, such as ligand-binding pockets.

Prof. Thomas Simonson will present, from the BIOS Research Group, BIOcomputing and Structure, École Polytechnique and the Centre national de la recherche scientifique

Free & open to the scientific community. Register at: sbgrid.org/webinars/

#sbgrid #structuralbiology #proteins #proteindesign #proteinengineering

Last updated 2 years ago

Lucas Nivon · @lucas_nivon
94 followers · 163 posts · Server mas.to

@Klausenhauser great work from @uwproteindesign who aren’t on yet

#proteindesign #Fediverse

Last updated 2 years ago

Itamar Kass · @IKass
3 followers · 8 posts · Server tooot.im

I finally have the time to write an introduction:
I am a , currently working in the industry. I have a long-standing interest in the study the correlation between the 3D structure and dynamics of proteins and their regulation mechanisms. thought my research I had used , , , FTIR, , , , and more.
When I have time, I enjoy to , specifically do with my kids.

#trailrun #run #proteindesign #docking #modelling #moleculardynamics #spr #xrayscattaring #nmr #biomed #scientist #structuralbiology

Last updated 2 years ago

IT News · @itnewsbot
1945 followers · 239228 posts · Server schleuss.online

‘The dark matter is just sitting there’: What’s standing in the way of AI for life sciences - Life sciences panelists at Madrona Venture Group’s Intelligent Application Summit... - geekwire.com/2022/the-dark-mat /lifesciences

#ai #alphafold #lucasnivon #rosettafold #proteindesign #cyrusbiotechnology #health

Last updated 2 years ago