How do mitochondria obtain the #ribonucleotides they need for organellar transcription?
Thomas MacVicar, Thomas Langer and colleagues show key fueling role of #mitochondrial #nucleoside diphosphate kinase #NME6 that phosphorylates #pyrimidine nucleosides
https://www.embopress.org/doi/full/10.15252/embj.2022113256
#ribonucleotides #mitochondrial #nucleoside #nme6 #pyrimidine
Broken Genes and Scrambled Proteins: How Radiation Causes Biological Damage https://hackaday.com/2023/01/24/broken-genes-and-scrambled-proteins-how-radiation-causes-biological-damage/ #reactiveoxygenspecies #non-ionizing #OriginalArt #pyrimidine #ioninzing #radiation #Featured #Interest #hydroxl #protein #radical #thymine #damage #x-ray #UV-B #dna #uv
#reactiveoxygenspecies #non #OriginalArt #pyrimidine #ioninzing #radiation #Featured #Interest #hydroxl #protein #radical #thymine #damage #x #uv #dna
Broken Genes and Scrambled Proteins: How Radiation Causes Biological Damage - If decades of cheesy sci-fi and pop culture have taught us anything, it’s that rad... - https://hackaday.com/2023/01/24/broken-genes-and-scrambled-proteins-how-radiation-causes-biological-damage/ #reactiveoxygenspecies #non-ionizing #originalart #pyrimidine #ioninzing #radiation #featured #interest #hydroxl #protein #radical #thymine #damage #x-ray #uv-b #dna #uv
#dna #uv #x #damage #thymine #radical #protein #hydroxl #interest #featured #radiation #ioninzing #pyrimidine #originalart #non #reactiveoxygenspecies
Happy to share our just accepted #review on #multitarget approaches for the #synthesis of #purine and #pyrimidine derivatives. From the #prebiotic/#abiotic origin of life to new #green #chemistry strategies for #drugdiscovery.
https://chemistry-europe.onlinelibrary.wiley.com/doi/epdf/10.1002/ejoc.202201288?utm_source=google&utm_medium=paidsearch&utm_campaign=R3MR425&utm_content=Chemistry
#pyrimidine #drugdiscovery #green #chemistry #review #synthesis #prebiotic #MultiTarget #purine