PLOS Biology · @PLOSBiology
4896 followers · 1531 posts · Server fediscience.org
#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm
#pyroptosis #plosbiology #inflammation #celldeath #gasdermins
PLOS Biology · @PLOSBiology
4897 followers · 1529 posts · Server fediscience.org
#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm
#pyroptosis #plosbiology #inflammation #celldeath #gasdermins
PLOS Biology · @PLOSBiology
4897 followers · 1524 posts · Server fediscience.org
#Gasdermins (GSDMs) are pore-forming proteins involved in #CellDeath & #inflammation. @jianbin_ruan explores a #PLOSBiology study of the evolution of GSDMs in metazoa, highlighting the role of GSDME in #pyroptosis. Primer: https://plos.io/3nyd4By Paper: https://plos.io/3p6klcm
#pyroptosis #plosbiology #inflammation #celldeath #gasdermins
PLOS Biology · @PLOSBiology
4892 followers · 1519 posts · Server fediscience.org
Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm
#plosbiology #caspase #gsdme #Amphioxus #pyroptosis #Gasdermin
PLOS Biology · @PLOSBiology
4891 followers · 1516 posts · Server fediscience.org
Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm
#plosbiology #caspase #gsdme #Amphioxus #pyroptosis #Gasdermin
PLOS Biology · @PLOSBiology
4887 followers · 1513 posts · Server fediscience.org
Characterization of #Gasdermin E-mediated #pyroptosis in the basal chordate #amphioxus reveals that #GSDME is transcriptionally regulated by IRF1/8, involved in bacteria-induced tissue damage, and inhibited by #caspase inhibitor #PLOSBiology https://plos.io/3p6klcm
#plosbiology #caspase #gsdme #Amphioxus #pyroptosis #Gasdermin
Achillebro👨🏼⚕️ · @Achillebro
133 followers · 68 posts · Server mstdn.scienceGreat paper from Kong et al. not all Gasdermins #GSDM are created equal. Great work to elucidate how the different splicing variants of #GSDMB contribute to #pyroptosis. Very elegant! https://www.science.org/doi/10.1126/sciimmunol.adg3196
The EMBO Journal · @embojournal
424 followers · 131 posts · Server sciencemastodon.com
Uptake-independent killing of macrophages by extracellular #Mycobacterium #tuberculosis aggregates
Chiara Toniolo et al show that Mtb aggregates evade #phagocytosis by inducing #macrophage #pyroptosis via a mechanism involving its type VII secretion system ESX-1 and surface lipid PDIM
#mycobacterium #tuberculosis #phagocytosis #macrophage #pyroptosis
Fawaz Alzaid, PhD · @DrFAlzaid
46 followers · 236 posts · Server mastodon.worldRT @Lo_Zanzi@twitter.com
#WeekendRead! #LocationLocationLocation! Neutrophils have #NoTimeToDie when sensing microbial ligands from phagosomes. But when the threat comes from the plasma membrane, a caspase-1, #GSDMD, #pyroptosis pathway is activated to drive #NETosis! @CellReports@twitter.com http://doi.org/10.1016/j.celrep.2022.111688
#WeekendRead #locationlocationlocation #notimetodie #gsdmd #pyroptosis #netosis
Bernhard Schermer · @cilib
352 followers · 413 posts · Server social.cologneWelcome to the expanding cell death community on #scienceMastodon! 🙂
#ScienceMastodon #celldeath #necroptosis #ferroptosis #pyroptosis
Bernhard Schermer · @cilib
307 followers · 350 posts · Server social.cologneGreat that you joined #ScienceMastodon! 🙂🙂🙂
Welcome to the masters of regulated cell death! 💀 ☠️
#celldeath #necroptosis #ferroptosis #pyroptosis #apoptosis #cilia #Sciencefediverse #DFG #biology #plants
#ScienceMastodon #celldeath #necroptosis #ferroptosis #pyroptosis #apoptosis #Cilia #ScienceFediverse #DFG #biology #Plants