Interview with Matt Kaeberlein
https://youtu.be/MSCrQYC9Alo?si=MbYl9ETXdOj_5aI3
Longitudinal lifestyle / environmental study ongoing.
Now recruiting for low-dose rapamycin study.
Dogs must be living in US & able to travel to 1 of 20 clinical partner sites. Other criteria: at least 7 yrs old & weigh 40 - 110 lbs.
Dog Aging Project website
https://dogagingproject.org/
Will there ever be a Cat Aging Project?
#dogs #aging #rapamycin #dogagingproject
#Rapamycin and Muscle Growth: A Review of the Glass Lab's use of Rapamycin to Reverse #Sarcopenia and Anabolic Resistance
#rapamycin #sarcopenia #antiaging
#IDMastodon #Immunology #oncologyresearch #Clinicalreview @Nature Understanding #mTORpathway & Mechanisms underlying the effects of #rapamycin on healthspan / lifespan . Role of mTOR inhibition on host #immunity & #CancerTherapy
📌 https://www.nature.com/articles/s43587-023-00416-y#Sec11
📌 https://www.nature.com/nataging
#IDMastodon #immunology #oncologyresearch #clinicalreview #mtorpathway #rapamycin #immunity #CancerTherapy
A study from 2019 "by UT Health San Antonio and collaborating institutions shows age-related decreases in blood flow to the brain and memory loss can be modified with the drug rapamycin.
This finding, if furthered, holds implications for aging in general and perhaps offers an avenue to prevent Alzheimer’s dementia in some people, said research first author Candice Van Skike, Ph.D., of UT Health San Antonio."
https://news.uthscsa.edu/study-rapamycin-prevents-age-related-brain-vascular-deterioration/
On LinkedIn, Alex Zhavoronkov is celebrating (?) publishing nonsense in #Oncoscience in a day using ChatGPT. Citing the EiC likely helped. The AI churned out text on Pascal’s wager in the context of Rapamycin that fails develops an argument linking religious belief to the merits of life extension.
I hope this is a sting and Alex doesn't stand by the inane content.
#ChatGPT #AIwriting #PredatoryJournals #Stings #LongevityMedicine #PascalsWager #Rapamycin #LinkedIn
#linkedin #rapamycin #pascalswager #longevitymedicine #stings #predatoryjournals #aiwriting #chatgpt #oncoscience
Unravelling effects of anti-aging drugs on C. elegans using liposome-mediated compound delivery
#rapamycin #preprint #aging #Celegans
🚨 Paper alert!
Yu-Xuan Lu and Jennifer Regan show sex specific differences in response to the #antiaging drug #rapamycin.
Press release:
âž¡https://www.age.mpg.de/communications/news/detail/do-women-age-differently-from-men
Original publication:
âž¡ https://www.nature.com/articles/s43587-022-00308-7
Yu Xuan Lu (not yet in the fediverse) and I are happy to share the publication of our work on sex differences in intestinal responses to the anti-#ageing drug #rapamycin, in the making for some time (more years than I care to calculate :)
#Rapamycin improves survival from an immune challenge in mice. Our recent meta-analysis on #aging in print now:
https://link.springer.com/article/10.1007/s11357-022-00691-4
Rapamycin not dietary restriction improves resilience against pathogens in mice: a meta-analysis
https://link.springer.com/article/10.1007/s11357-022-00691-4
Hi everyone - preparing for the perhaps inevitable move! The @LammingLab at #uwmadison studies how nutrients like #protein and #BCAAs regulate #healthspan and #aging via #biological mechanisms like #mTOR signaling. We also study how the #mTOR inhibitor #rapamycin might be useful for age-related disease.
#rapamycin #MTOR #biological #aging #healthspan #BCAAs #protein #uwmadison
Maternal sleep apnea may contribute to autism-like traits in rats
https://www.spectrumnews.org/news/maternal-sleep-apnea-may-contribute-to-autism-like-traits-in-rats/
#dendrites #rapamycin #synapses #autism #sleep #News #rats #sex
#dendrites #rapamycin #synapses #autism #sleep #news #rats #sex
Autism model mice develop typical social and motor behaviors after drug treatment
https://www.spectrumnews.org/news/autism-model-mice-develop-typical-social-and-motor-behaviors-after-brief-drug-treatment/
#tuberoussclerosis #Purkinjecells #mousemodels #cerebellum #rapamycin #autism #News #TSC1
#tuberoussclerosis #Purkinjecells #mousemodels #cerebellum #rapamycin #autism #news #TSC1
Synaptic overgrowth, hyperconnectivity may define autism subtype
https://www.spectrumnews.org/news/synaptic-overgrowth-hyperconnectivity-may-define-autism-subtype/
#connectivitytheory #connectivity #rapamycin #autism #News #TSC2 #MRI
#connectivitytheory #connectivity #rapamycin #autism #news #TSC2 #mri
Molecular overlap links tuberous sclerosis, fragile X
https://www.spectrumnews.org/news/molecular-overlap-links-tuberous-sclerosis-fragile-x/
#tuberoussclerosis #fragileXsyndrome #geneexpression #spokenversion #cerebellum #rapamycin #News #FMRP #TSC1
#tuberoussclerosis #fragileXsyndrome #geneexpression #spokenversion #cerebellum #rapamycin #news #FMRP #TSC1