Common ancestors of #bats were omnivorous, according to resurrection of ancestral sweet #receptors.
https://phys.org/news/2023-08-common-ancestors-omnivorous-resurrection-ancestral.html
#bats #receptors #genomics #sensing #tas1_r2
A new perspective in #protein research focuses on #disordered areas.
https://phys.org/news/2023-07-perspective-protein-focuses-disordered-areas.html
#protein #disordered #membrane_channels #receptors
Designing synthetic #receptors for precise #cell control.
#biosensors #signalling #chemotaxis
https://phys.org/news/2023-05-synthetic-receptors-precise-cell.html
#receptors #cell #biosensors #signalling #chemotaxis
#Cellular #traffic controllers caught managing flow of #signals from #receptors.
https://phys.org/news/2023-05-cellular-traffic-caught-receptors.html
#cellular #traffic #signals #receptors
Referenced link: https://phys.org/news/2023-05-cellular-traffic-caught-receptors.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-05-cellular-traffic-caught-receptors.html
Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1654138838028091395#m
Cellular traffic controllers caught managing flow of signals from #receptors @CellCellPress https://linkinghub.elsevier.com/retrieve/pii/S0092867423004142 https://phys.org/news/2023-05-cellular-traffic-caught-receptors.html
Molecular dynamics simulations of the dimer of AMPA-type glutamate receptor binding domains from DE Shaw and colleagues. Seems to confirm some of our earlier functional work on desensitization (including one of the first mutants we published in 2012!), and also the transient encounters of glutamate on its way to the binding site. 190 µs of simulations!
https://www.sciencedirect.com/science/article/pii/S0969212623000965
#ionchannels #glutamate #MolecularDynamics #electrophysiology #receptors
#IonChannels #glutamate #moleculardynamics #electrophysiology #receptors
Unexpected early evolution of acid sensing ion channels, before brains, from Tim Lynagh and collaborators.
#IonChannels #receptors #evolution #bilateran
#Scientists at St. Jude Children’s Research Hospital added a #molecular anchor to #chimeric #antigen #receptors (#CARs), increasing the anti-cancer activity of cellular #immunotherapies in #cancer models.
#Biology #Medical #sflorg
https://www.sflorg.com/2023/02/bio02052305.html
#scientists #molecular #chimeric #antigen #receptors #cars #immunotherapies #cancer #biology #medical #sflorg
RT @miguel_matilla
In our recent paper in @mbiojournal we examine the role of #auxins as #agonists and #antagonists of bacterial #signal #transduction #receptors. We also investigate the emergence of an auxin recognition motif in #plant-associated #bacteria. @BlastMeetings
#auxins #agonists #antagonists #signal #transduction #receptors #plant #bacteria
@NeuroDrugDoc thanks for addressing. It’s worth adding that there are #GabaA #receptors that don’t have gamma subunit and cannot be modulated by BDZs
Why does the Alzheimer’s brain become insulin-resistant?
#Health #Alzheimer #Insulin #Dementia #Physiology #Neuroscience #Hormones #Brain #Drugs #Proteins #Blood #Neurons #Receptors #Pancreas #BloodVessels #InsulinResistance
https://the-14.com/why-does-the-alzheimers-brain-become-insulin-resistant/
#health #alzheimer #insulin #dementia #physiology #neuroscience #hormones #brain #drugs #proteins #blood #neurons #receptors #pancreas #bloodvessels #insulinresistance
Why does the Alzheimer’s brain become insulin-resistant?
#Health #Alzheimer #Insulin #Dementia #Physiology #Neuroscience #Hormones #Brain #Drugs #Proteins #Blood #Neurons #Receptors #Pancreas #BloodVessels #InsulinResistance
https://the-14.com/why-does-the-alzheimers-brain-become-insulin-resistant/
#health #alzheimer #insulin #dementia #physiology #neuroscience #hormones #brain #drugs #proteins #blood #neurons #receptors #pancreas #bloodvessels #insulinresistance
"5-HT1A and 5-HT2B receptor interaction and co-clustering regulates serotonergic neuron excitability"
https://www.biorxiv.org/content/10.1101/2022.12.09.519723v1
#dynamics #receptors #serotonin #brain #neuro #neuroscience #arxivfeed
Xiong, Q., Cao, L., Ma, C. et al. Close #relatives of #MERS-CoV in #bats use #ACE2 as their functional #receptors. #Nature (2022). https://doi.org/10.1038/s41586-022-05513-3 {#NeoCoV}
#relatives #mers #bats #ace2 #receptors #nature #neocov
Examining previously unknown #molecular mechanisms for #environmental adaptation in #plants.
#membrane #transport #receptors #ubiquitin @acclimation@twitter.com
https://phys.org/news/2022-11-previously-unknown-molecular-mechanisms-environmental.html
#molecular #environmental #plants #membrane #transport #receptors #Ubiquitin
RT @MoltagDK@twitter.com
Margot Ernst group at @MedUni@twitter.com newest review discusses the function of #cannabinoids on cys-loop #receptors, including their clinical use for the treatment of #epilepsy, #ChronicPain and other #neuropsychiatric conditions. Congratulations to the group! https://tinyurl.com/j5b7j9tw
#neuropsychiatric #chronicpain #epilepsy #receptors #cannabinoids
Referenced link: https://phys.org/news/2022-08-exploring-limits-protein-coupled-receptors.html
Discuss on https://discu.eu/q/https://phys.org/news/2022-08-exploring-limits-protein-coupled-receptors.html
Originally posted by Phys.org / @physorg_com@twitter.com: https://twitter.com/physorg_com/status/1559181886848655365#m
Exploring the limits of G protein-coupled #receptors @istaustria @NatureComms https://www.nature.com/articles/s41467-022-32390-1 https://phys.org/news/2022-08-exploring-limits-protein-coupled-receptors.html