Stop withholding GLP1-RAs from #Dialysis patients! #Renalism at its best…

#Semaglutide may reduce risk for atherosclerotic CVD among adults with obesity https://www.healio.com/news/endocrinology/20230602/semaglutide-may-reduce-risk-for-atherosclerotic-cvd-among-adults-with-obesity

@leigh @grivettcarnac

And also can be (should be) used in people with kidney disease or dialysis https://www.ontariohealth.ca/sites/ontariohealth/files/2022-04/PaxlovidClinicalGuide.pdf (PDF) and data to back it up https://journals.lww.com/cjasn/abstract/9900/early_experience_with_modified_dose.71.aspx (made in #Ottawa push to counter Health Canada #Renalism)

@mike_johansen in the dialysis world we mostly live and breathe in off-label prescribing environment

#Renalism

plus of course - the #Renalism continues

VV116 = oral #Remdesivir, no reason to exclude CKD patients

Same with #Paxlovid, as we have shown here https://journals.lww.com/CJASN/Fulltext/2022/08000/Prescribing_Nirmatrelvir_Ritonavir_for_COVID_19_in.22.aspx and https://journals.lww.com/cjasn/Abstract/9900/Early_Experience_with_Modified_Dose.71.aspx

@ChristosArgyrop

My unhappiness will persist in that the authors do not even bother talking about kidney function

#Renalism #Paxlovid #Covid

Have a look at table 1 2/2

#Ageism and #renalism in action

veterans with #CKD who experience #ACS less likely than those without CKD to receive clinically indicated invasive cardiac care leading to associated increased mortality …

https://journals.lww.com/jasn/abstract/9900/utilization_and_outcomes_of_clinically_indicated.40.aspx

@mike_johansen @colby thanks for the #Renalism tag - but their CKD numbers don’t make any sense to me - https://med-mastodon.com/@hswapnil/109609066119606179

Good news in this study. I'm uncertain whether this should have been run against Paxlovid or placebo as Paxlovid hasn't been shown to improve symptomatic end points (I'm not sure I believe it doesn't though).

#Renalism #MedMastodon #IDMastodon

https://www.nejm.org/doi/full/10.1056/NEJMoa2208822?query=recirc_mostViewed_railB_article

The oral #Remdesivir compared to #paxlovid on a non-inferiority trial from …Shanghai China with ο B1.1.529 https://www.nejm.org/doi/10.1056/NEJMoa2208822?s=09

Let’s look at this from the #Renalism POV
1/ 🧵