Pearl: in membranous LN patients who stain positive for Exostosin 1 and Exostosin 2 antigens, they tend to have a better long term kidney outcome than those membranous LN patients who stain negative!
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Studying lupus nephritis tonight!
Exostosin 1 and Exostosin 2 antigens are transmembrane proteins in podocytes that are over expressed in the setting of membranous nephropathy and can be seen in 30% membranous lupus nephritis!
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#RheumTwitter #Lupus #lupusnephritis #rheumboards