Issue 14:
Highlight on #ROR1 and #pancreatic #malignancy
Review on viral recognition and #antiviral #interferon response
#Autophagy news from plants and mammals
How #p97 disassembles a regulatory protein complex
Developmental #axon pruning by a #phospholipid #scramblase
Cover: Elisa Nerli, Caren Norden and colleagues
#ror1 #pancreatic #malignancy #Antiviral #interferon #autophagy #p97 #axon #phospholipid #scramblase
#YAP/#BRD4-controlled ROR1 promotes tumor-initiating cells and #hyperproliferation in #pancreaticcancer
Masaya Yamazaki et al show that #ROR1 marks an aggressive partial #EMT cell cluster and enhances #PDAC proliferation via c-#Myc/#E2F/#AURKB signaling
#yap #hyperproliferation #pancreaticcancer #ror1 #EMT #pdac #myc