My Dresden colleagues have recently published a paper.
Carlotta Mayer (@c_ma_yer on the cross site) shows that #hepatocytes react to increased #bile #pressure by forming the #apical projections called bulkheads. This is also observed in #human #liver when bile pressure is increased to a pathological level. Upon further increase of bile pressure, bulkheads no longer hold the #canaliculi shape and form #rosettes.
#CellBiology #CellPolarity
https://doi.org/10.15252/embr.202357181
https://twitter.com/ZerialLab/status/1686028788658847744?s=20
#hepatocytes #bile #pressure #apical #human #liver #canaliculi #rosettes #cellbiology #cellpolarity
the past couple years I experimented with tweaking the batter recipe we used, and they were always chewy or burned. so this year I went back to our original and what do you know - perfection. this batter also cooks a bit faster so that didn’t take quite as long!
#cookieseason #holidays #rosettes