RT @proteincapsid
1/8 🧵 How does the complex Rotavirus assemble? Our team aimed to uncover the process behind this large non-enveloped virus with 3 protein shells enclosing a multi-segmented dsRNA genome. A purpose-built nanomachine, its capsid assembly remained a mystery. #Virology #Rotavirus

"Here, we demonstrate the induction of both systemic and mucosal antibody responses against HuNoV in suckling mice using recombinant Rhesus rotaviruss expressing HuNoV VP1 or P domain."
#MucosalImmunology #Immunology #rotavirus

https://www.pnas.org/doi/10.1073/pnas.2214421120

#Rotavirus is responsible for most cases of severe diarrhea in children under five years of age, mainly in developing countries

📌 Rotavirus causes more than 200,000 deaths per year worldwide

📌 There is a safe and effective #vaccine

📌 In 🇮🇹 this vaccine is free of charge for all infants (An Italian proverb says "Chi ha il pane non ha I denti" Literally: who has bread doesn't have teeth")

http://outbreaknewstoday.com/rotavirus-even-with-the-availability-of-vaccines-it-is-still-responsible-for-most-cases-of-severe-diarrhea-in-children-under-five-years-of-age-26517/

I nostri amici #novax tornano a deliziarci con improbabili paragoni. Statistiche buttate a caso, eventi paragonati senza senso, la logica che va in vacanza
#COVID19 #vaccino #rotavirus #suina #nessunacorrelazione #percentuali #statistica

https://www.bufale.net/limprobabile-paragone-del-vaccino-covid19-con-rotavirus-e-suina/

Review of the health impact of the oral #rotavirus #vaccine program in children under 5 years in Australia: 2006 – 2021

📌 The rotavirus vaccine program has resulted in a significant decrease in the burden of rotavirus disease for most children.

📌 No evidence for the emergence of nonvaccine serotypes and/ or replacement serotypes in during the vaccine era

📌 the health impact for young children and consequent cost-savings of the rotavirus vaccine program have been high

https://www.sciencedirect.com/science/article/pii/S0264410X22015250?dgcid=rss_sd_all

👉 In 2019, human rotavirus vaccine (HRV) and pneumococcal polysaccharide protein D-conjugate vaccine (PHiD-CV) together averted

📌 nine cases of severe disease each minute

and

📌 one child death every 4 minutes

in Gavi-supported countries

#Rotavirus
#Pneumococcal
#Vaccine
#Gavi (https://www.gavi.org)

https://www.tandfonline.com/doi/full/10.1080/21645515.2022.2135916

📌 Let's talk about #rotavirus?

Long-term surveillance of rotavirus vaccination after implementation of a national immunization program in Finland (2008–2018)

Rotavirus gastroenteritis incidence decreased significantly (inpatient rotavirus gastroenteritis admissions declined by as much as 96% in children < = 5 years) soon after implementation of RV vaccination ( coverage rate > 90%) and remained low in all age groups during the 10 years following …

📌 What else?

https://www.sciencedirect.com/science/article/pii/S0264410X22005849

The big question now is, is everyone on this #plane getting #rotavirus because someone hoarked in the lav and they are holding us all in here while they remove the passenger and disinfect.

New #research using our #Population #OpenData - #Spatial distribution of #rotavirus #immunization coverage in #Ethiopia: a #geospatial analysis using the #Bayesian approach - #HealthAccessibility #SDG3 https://doi.org/10.1186/s12879-022-07825-1

#PCV13 and #rotavirus vaccination were NOT associated with an increased risk of #Kawasaki disease in children <2 years of age

https://publications.aap.org/pediatrics/article-abstract/doi/10.1542/peds.2022-058789/189926/Kawasaki-Disease-Following-the-13-valent?redirectedFrom=fulltext