Hi #ScienceMastodon! Check out the last Research Highlight from Issue 17 of JCS: Ke Hu and colleagues at Arizona State University mess with microtubule-associated proteins in Toxoplasma gondii to answer whether the distinct helical motility of this apicomplexan parasite arises from the spiral arrangement of its remarkably stable cortical microtubules.
#CellBiology #microtubules #parasitology

Function follows form of cortical microtubules in Toxoplasma gondii
https://journals.biologists.com/jcs/article/136/17/e136_e1702/327904/Function-follows-form-of-cortical-microtubules-in

👀 How do we study #cancer? You're watching the cryosectioning of a liver biopsy containing metastatic colon tumor. The staining allows for the visualization of cellular abnormalities & tissue architecture > https://www.instagram.com/p/CxCtG4-Mpg4/

Thanks to Ilaria Mulas from our Computational Biology Research Centre!

#science #sciencemastodon #biology #lifesciences #humantechnopole

Astronomers have long debated what kind of chemistry might serve as a bona fide alien biosignature. With the launch of the James Webb Space Telescope, those ideas may be put to the test.

✍️ Elise Cutts

https://knowablemagazine.org/article/physical-world/2023/how-to-detect-life-on-exoplanets?utm_source=mastodon&utm_medium=post&utm_campaign=originals

#KnowableMagazine
#ScienceMastodon
#astronomy
#JWST

How do patients contribute to change and to shifting mindsets? What information lies still undiscovered in the genes? A study of the recent history of medicine and a look to the future – new #ERCStG projects at #CharitéBerlin. @berlinnovation

👉 https://www.charite.de/en/service/press_reports/artikel/detail/erc_starting_grants_for_two_charite_researchers/

#Medicine #ScienceMastodon #Research #ResearchFunding #StartingGrants #CharitéHistory
#Genomics #CharitéBiomedicine

Wie tragen Patient:innen zu Wandel und Umdenken bei? Und: Welche Informationen liegen noch unentdeckt in den Genen? Ein Blick in die jüngere #Medizingeschichte, ein Blick in die Zukunft der #Medizin: zwei neue #ERCStG an #CharitéBerlin & @berlinnovation. Gratulation den Grantees!! @ERC_Research @pietznerm

👉 https://www.charite.de/service/pressemitteilung/artikel/detail/erc_starting_grants_fuer_zwei_forschende_der_charite/

#Medicine #Research #ResearchFunding #StartingGrants #ScienceMastodon #Science #CharitéHistory #Genomics #CharitéBiomedicine

Wow, I just discovered the process of adding an author to a paper after review, at Wiley.

Who hurt you, Wiley? I think getting German citizenship was easier 😂
#sciencemastodon #sciencepublishing

Neuroblastoma is a #cancer in children that is sometimes benign, but can also be very aggressive. Researchers from #CharitéBerlin & @MDC_Berlin now show: Specific patterns of DNA alterations in #neuroblastoma cells reflect the different aggressiveness of this pediatric #tumor. The results could provide a starting point for a more targeted approach to treatment.
https://www.charite.de/en/research/paper_spotlight/2023/new_findings_on_the_biological_processes_behind_neuroblastoma_risk_differences/

#Medicine #Research #CharitéPaper #CharitéOncology #ScienceMastodon #MedMastodon

A systematic review by #CharitéBerlin and University Aarhus in Denmark in
JAMA Psychiatry has shown that antidepressants are effective and safe in depressed people with physical health problems such as #cancer, #diabetes, #stroke or heart attack.

👉 https://www.charite.de/en/service/press_reports/artikel/detail/antidepressant_use_in_people_with_both_physical_health_problems_and_depression/

#medicine #science #research #ScienceMastodon #MedMastodon #CharitéPaper #Psychology

Antidepressiva sind wirksam und sicher – auch bei Menschen mit körperlichen Erkrankungen wie #Krebs, #Diabetes, nach #Schlaganfall oder #Herzinfarkt. Das zeigt eine systematische Übersichtsarbeit von #CharitéBerlin und Universität Aarhus in Dänemark in JAMA Psychiatry.

👉 https://www.charite.de/service/pressemitteilung/artikel/detail/antidepressiva_bei_koerperlichen_erkrankungen_und_gleichzeitiger_depression/

#Medizin #Forschung #Wissenschaft #CharitéPaper #ScienceMastodon #MedMastodon #psychology

Hi #ScienceMastodon! Today's Research Highlight from JCS features work from Marijeta Kralj and colleagues at the Ruđer Bošković Institute and GENOS Glycoscience Research Laboratory in Croatia. In their paper, they explore why the drug salinomycin selectively targets cancer cells in epithelial-to-mesenchymal transition, a process associated with insidious cancer stem cells.
#CellBiology #cancerbio

Salinomycin hits EMT cancer cells where it hurts, at the Golgi
https://journals.biologists.com/jcs/article/136/17/e136_e1701/326604/Salinomycin-hits-EMT-cancer-cells-where-it-hurts

🤝 Welcome aboard!

🎉 We're thrilled to announce that Marino Zerial has officially taken the helm as the new Director of Human Technopole, leading the way in advancing #lifesciences research

#science #sciencemastodon #humantechnopole

🔬 How to unveil a Chlamy organisation without expensive instruments and specific training?

Our Pigino Group with the University of Geneva, developed an ExM-based protocol to visualise the 3D ultrastructural organisation of Chlamydomonas reinhardtii by using conventional optical light microscopes.

✌️ Published in Bio-protocol and available now to the research community.

https://humantechnopole.it/en/news/ultrastructure-expansion-microscopy-details-chlamy-native-organisation/

#lifesciences #humantechnopole #microscopy #science #sciencemastodon

I just learned about the COOLEST program! It's called "Letters to a Pre-Scientist" and if you sign up, you volunteer to be a pen pal to a kid and help them get excited for a career in a #STEM field! It sounds like a wonderful opportunity for #ScienceMastodon to do some good in the world. The program is open to anyone in STEM over 18, all around the world. Please share this post, they need more volunteers!

https://prescientist.org/volunteers/

#science #space #Physics #Math #Dev #IndieDev #medicine #Research

📊 New to the world of #statistics?

Watch the interview with Michela Carlotta Massi, postdoc at our Health #DataScience Centre, who shares her journey in crafting new statistical approaches for precision #medicine

https://www.youtube.com/watch?v=3R5O91tH3N4

#science #sciencemastodon #stem #womeninstem #humantechnopole #lifesciences

To help birds and insects, cultivate native gardens 🌱

Entomologist Doug Tallamy has this advice for the readers of his book Nature’s Best Hope, geared toward kids:

"Feel empowered. Feel like there are things they can do where they live. If they live in the middle of a city with no land at all, they can get into container gardening. They can become activists. They can volunteer at preserves that are in their city."

Read the Q&A: https://knowmag.org/45QOXOS

#KnowableMagazine
#ScienceMastodon

For the latest Research Highlight from JCS, we have a Short Report from Kenta Terai and colleagues at Kyoto University and the RIKEN Center for Brain Science in Japan. Using a series of Madin–Darby canine kidney (MDCK) cell lines with single and combined knockouts of the four ErbB receptors, the authors dissect roles of each receptor in complex epithelial cell behaviors. Learn more here: How ErbB receptors keep epithelial tissues in shape
https://journals.biologists.com/jcs/article/136/16/e136_e1603/325950/How-ErbB-receptors-keep-epithelial-tissues-in

#CellBiology #ScienceMastodon

I created a free #K12 interactive #science quiz for #students to discover which Order a Mammal belongs to. If you'd like to beta test it and let me know if you find glitches, I'd appreciate it. I've stared at the screen for too long and am no longer seeing the branching questions objectively. The plugin limits me to a max of 25 categories, so I had to get creative. TIA for the feedback.
https://handinhandhomeschool.com/teaching/science/mammal-quiz/ ‎

#ScienceMastodon #Biology #Animals #Teachers

The extraordinary case of the ferocious female moles: Their genital anatomy, musculature and aggressiveness have made them a model for studying the phenomenon of female masculinization — and demonstrate that sometimes, it’s not easy to tell the difference between male and female

Read more in:

👉 @KnowableMag https://arevie.ws/FierceFemales_KM
👉 Knowable en español https://arevie.ws/FierceFemales_KEE
👉 Annual Review of Animal Biosciences https://arevie.ws/FierceFemales

#KnowableMagazine
#ScienceMastodon

👨‍🔬 From ant genomics to human gene expression, explore the scientific journey of Rodrigo Pracana - Functional Genomics Computation Scientific Service Unit - and gather insights about HT research.

"I was warned from the start that science can be a rollercoaster of emotions, with the worst of disappointments and the best achievements happening on the same day. Don’t let it get to you and enjoy the ride!"

https://humantechnopole.it/en/news/exploring-ht-research-with-rodrigo-pracana-from-genomics/

#science #sciencemastodon #lifesciences #humantechnopole #genomics

Hi #ScienceMastodon! Today's Research Highlight from JCS is a great example of how publishing studies that re-test old hypotheses with modern, more sensitive methods can address #reproducibility. Sabrina Holland and Gianluca Gallo from Temple University in Pennsylvania reexamine whether actin dynamics in growing axons are as much of a drain on neuronal energy homeostasis as previously reported.

Revisiting actin dynamics and energy homeostasis in growing neurons
https://journals.biologists.com/jcs/article/136/16/e136_e1602/325934/Revisiting-actin-dynamics-and-energy-homeostasis