Supplementation with Amino Acid Serine Eases Neuropathy in Diabetic Mice

'We were surprised that dialing up and down a non-essential amino acid had such a profound effect on metabolism and diabetic complications,” says senior author Christian Metallo ... “It just goes to show that what we think of as dogma can change under different circumstances, such as in disease conditions. '

https://today.ucsd.edu/story/serine-eases-neuropathy-in-diabetic-mice

#neuropathy #serine
#NaturalProducts

An #atlas of substrate specificities for the #human #serine /#threonine #kinome
#proteomics
https://doi.org/10.1038/s41586-022-05575-3