Key findings:
- age and sex had a significant effect on the 99th percentile of serum hs-cTnT concentration in both cohorts
- hospitalization is associated with higher hs-cTnT levels in in most age groups than in individuals in the general population, even in patients without diagnosed or suspected heart disease
- age- and sex-specific hs-cTnT reference values may be beneficial for hospitalized patients
3/3
#ctnt #Troponin #ami #Ampel #cdss #sexbias #patientsafety
Unadjusted Creatinine Hinders Females to Get New Liver
- Standard mathematical conversion of #creatinine disadvantages females in liver transplantation prioritization
- We investigated options to reduce this gender inequality
- We identified 72 of 650 (11%) females with an original #MELD score < 20, for whom the adjusted female-as-male MELD score would be >20, thus giving them a better chance to receive a #Liver #Transplant
#creatinine #meld #liver #transplant #ltx #sexbias #genderbias #cdss #Ampel
Our recent study about troponin thresholds (https://doi.org/10.3390/jcm10235508) shows the large differences in age- and sex-specific reference ranges. Young women are systematically underdiagnosed. The study by Arslani & Tontsch et al (described before) now suggests that this may lead to increased mortality in young women.
Gender and age-specific adjustment of troponin thresholds, is easy to accomplish, has low costs, and is likely to save lives.
#SexBias #Troponin #AMI #CDS #CDSS #AMPEL
2/2
#sexbias #Troponin #ami #cds #cdss #Ampel
RT @MadhviM@twitter.com
‼️Interested in how and why the immune response differs between men and women? ‼️
Happy to share our latest review article👇 on the #sexbias in #lymphocytes and it’s implications for #autoimmune diseases @KatyCDodd@twitter.com @FrontImmunol@twitter.com
https://www.frontiersin.org/articles/10.3389/fimmu.2022.945762/full
#sexbias #Lymphocytes #autoimmune