Nice papers that #neutrophils can also be epigenetically reprogrammed by infection - stemming from effects on stem cells.

Both use #zebrafish as model

#Shigella: https://www.science.org/doi/full/10.1126/sciadv.adf9706

#Salmonella: https://www.science.org/doi/10.1126/sciadv.adf9904
#trainedimmunity #immunology #epigenetics

It’s summer and that means disturbing swim advisories. Here’s our top 5 - Enlarge / A 2-year-old enjoys the spray of water in a splash pad in Los... - https://arstechnica.com/?p=1949894 #healthdepartment #clevelandclinic #e.colio157 #norovirus #shigella #science #giardia #health #crypto #safety #lakes #water #pool #cdc

Ars Technica: It’s summer and that means disturbing swim advisories. Here’s our top 5 https://arstechnica.com/?p=1949894 #Tech #arstechnica #IT #Technology #healthdepartment #clevelandclinic #E.coliO157 #Norovirus #shigella #Science #Giardia #Health #crypto #safety #lakes #water #pool #CDC

Same #protein, different #shape explains protein's effectiveness against #bacteria.

#Shigella #gasdermin

https://phys.org/news/2023-03-protein-effectiveness-bacteria.html

Referenced link: https://phys.org/news/2023-03-tracking-emergence-extensively-drug-resistant-shigella.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-03-tracking-emergence-extensively-drug-resistant-shigella.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1637844823997595649#m

Tracking the emergence of an extensively drug-resistant #Shigella sonnei strain in France @institutpasteur @NatureComms https://www.nature.com/articles/s41467-023-36222-8 https://phys.org/news/2023-03-tracking-emergence-extensively-drug-resistant-shigella.html

The spread of #Shigella depends more on climate factors than assumed. These findings publ.@LancetGH involving authors from the Infectious Disease Epidemiology Dpt @BNITM_de can help prioritise risk populations in Sub-Saharan #Africa 4 control measures e.g. http://bit.ly/3J07dwZ
---
RT @LancetGH
From the March issue: Spatiotemporal variation in risk of Shigella infection in childhood: a global risk mapping and prediction model using indivi…
https://twitter.com/LancetGH/status/1630153961767354370

#Shigella
#NewYorkCity
#Manhattan
#Nolita
#ThePuckBuilding
#Puck
#KushnerProperties
#EruvRoof
#JewishSabbath
#BriceDailyPhoto

FYI, The U.S. Centers for Disease Control and Prevention (CDC) is warning the public about a rising number of “extensively drug-resistant” (XDR) shigella bacteria infections, also known as shigellosis.

A group local to San Francisco who were instrumental in addressing the MPX outbreak, are monitoring the situation in California.

#HeadsUp #Shigella #Drugresistant #risingcases

https://www.npr.org/2023/03/03/1160584630/shigella-antibiotic-resistant-diarrhea

CDC warns of increase in extensively drug-resistant shigellosis, a serious gut bacteria. Additionally, shigella can spread this resistance to other gut bacteria.

Many of the recent shigella outbreaks have occurred among the unhoused population and among Men who have Sex with Men (MSM).

https://emergency.cdc.gov/han/2023/pdf/CDC_HAN_486.pdf

#shigella #cdc #AntibioticResistance #msm #Sti

Well. we know from past performances of the CDC that by the time they catch on it's too late. So, heads up, everyone?

"CDC Sounds the Alarm: A Diarrhea Superbug Is Resisting Drugs and Spreading Fast" https://gizmodo.com/cdc-advisory-shigella-drug-resistant-bacteria-1850164899 #Shigella #antibiotics #antibioticoveruse

Les infections par des Shigella résistantes augmentent de façon inquiétante aux États-Unis et en Europe https://www.futura-sciences.com/sante/actualites/bacteries-infections-shigella-resistantes-augmentent-facon-inquietante-etats-unis-europe-10376 #bactéries_multirésistantes #bactéries #santé_publique #infection #étatsunis #europe #1st_revue #0_archivebox #2nd_frm #shigella #antibiorésistance #shigelloses

CDC issues warning over an increase of drug-resistant bacteria

‘There are limited antimicrobial treatments available for these particular drug-resistant strains of Shigella and it’s also easily transmissible, warned the CDC in the Friday advisory. It’s also able to spread antimicrobial resistance genes to other bacteria that infect the intestines’

#science #medicine #health #DrugResistance #CDC #shigella

https://edition.cnn.com/2023/02/25/health/cdc-shigella-health-advisory/index.html

New research article in The Lancet Infectious Diseases>

Genomic reconstruction and directed interventions in a multidrug-resistant #Shigellosis outbreak in Seattle, WA, USA: a genomic surveillance study

https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00879-9/fulltext

#Shigella #AMR

New research article in The Lancet Infectious Diseases>

Emergence of extensively drug-resistant and multidrug-resistant #Shigella flexneri serotype 2a associated with sexual transmission among gay, bisexual, and other men who have sex with men, in England
https://www.thelancet.com/journals/laninf/article/PIIS1473-3099(22)00807-6/fulltext

#AMR

"Our findings underscore the importance of cell death in defense against intracellular bacterial pathogens and provide an example of how layered and hierarchical immune pathways can provide robust defense against pathogens that have evolved a broad arsenal of virulence factors."

#Shigella #HostPathogen #CellDeath #Apoptosis #InnateImmunity #Pathogen #Microbiology #Immunology

https://elifesciences.org/articles/83639

@SteveM2020 @jaymerryfield
Exactly… access to clean water and waste treatment are basic rights.
When I pass encampments I wonder how we can provide those effectively for people where they are, rather than breaking up their homes and making them move.
#yeg #houseless #shigella

Edmonton #Shigella outbreak rises to 173 cases http://outbreaknewstoday.com/edmonton-shigella-outbreak-rises-to-173-cases-173/ Shigella is a disease that’s commonly associated with diarrhea, as well as fever, nausea and stomach cramps. It can cause severe illness, resulting in hospitalization and it spreads when someone comes into contact with fecal matter from an infected person and also by eating food contaminated with the bacteria.