Gestern wurde ich auf einen Artikel zum Thema "Absetz- und Rebound-Phänomene bei Antidepressiva" aufmerksam gemacht.

Tja, wenn ich mir darin die Tabelle 2 anschaue, dann wundert mich gar nichts mehr. Eine Vielzahl der Symptome kann ich seit fast 2 Wochen bei mir beobachten, zum Glück mit stark rückläufiger Tendenz

#SNRI #Venlafaxin #absetzen

https://www.aerzteblatt.de/archiv/207288/Absetz-und-Rebound-Phaenomene-bei-Antidepressiva#group-5

Tag 19 meiner #Venlafaxin #SNRI Reduktion/Absetzung und damit Tag 5 ganz ohne

Die ersten 15 Tage hatte ich keine ungewöhnlichen Symptome, aber seit vorgestern bemerke ich etwas, das zu den bekannten "Entzugserscheinungen" gehört: Gesteigerte Unruhe und je nach Kopfbewegung ein seltsam raschelndes/knisterndes Geräusch in den Ohren

Soll nach spätestens zwei bis drei Wochen vergehen... darauf setze ich

PSA

I'm down to ~18.75 mg of venlafaxine daily now, using 37.5 mg pills cut in half.

Next week, I will be decreasing this even further to ~9.375 mg, using quarters.

I will thereafter start staggering days to finally get off this ✊

#MentalHealth #SNRI #depression #venlafaxine

I’ve now been taking #Venlafaxine (#Effexor) for three days. Objective: #migraine relief (and perhaps #ADHD relief too). #SNRI which is prescribed for depression but also has proven highly effective in trials for anxiety, migraine (especially vestibular) and ADHD. Side effects are limited and similar to Fluoxetine or Sertraline. The migraine effects were found in studies to be virtually the same as Amitriptyline, but with less (and better tolerated) side effects.

I’ve now been taking #Venlafaxine (#Effexor) for two days. Objective: #migraine relief (and perhaps #ADHD relief too). #SNRI which is prescribed for depression but also has proven highly effective in trials for anxiety, migraine (especially vestibular) and ADHD. Side effects are limited and similar to Fluoxetine or Sertraline. The migraine effects were found in studies to be virtually the same as Amitriptyline, but with less (and better tolerated) side effects.

Quick update

I've been very gradually coming off my daily Serotonin-Noradrenaline Reuptake Inhibitor (SNRI) - venlafaxine - for a while now.

I'd been up to 300 mg daily, so naturally I've been reducing it very slowly.

I.e., 300 to 225 to 150 to ~112.5 to ~75 to ~56.25.

I will shortly be decreasing it further to ~37.5 then ~18.75.

I'll then either start taking it every other day or possibly try dropping off entirely if possible without noticeable effects.

#SNRI #MentalHealth

Began my day at 5:45am with usual 200mg #Pristiq and commenced #Vyvanse 30mg. Oddly reassured by name of pharmaceutical company, #Takeda. Thank you interest in Japanese history for this irrational positive bias.

I followed this with my standard breakfast of 1 double shot flat white on BonSoy, muesli with fresh apple and BonSoy, then another double shot flat white on BonSoy.

No notable interaction between #SNRI and stimulant medications so far but slightly bitter taste in my mouth; a quick interweb search tells me this is not uncommon for Vyvanse.

12 years of #Pristiq at 200mg/day will - after recent review and evaluation - be augmented with #Vyvanse from tomorrow, starting at 30mg/day.

Adult diagnoses for Asperger’s (2010) and #ADHD is curious, if not bittersweet … if only for teenage or adolescent diagnosis. If only for early treatment and therapy; the family of origin is what it is and so it was not to be.

Will this new pharmacological scaffolding around my brain be effective? How will it interact with the #SNRI I currently take? Time will tell I guess; I hope to no longer misplace quite so much of it.