We used #parallelcomputing and #biophysical #simulations to go from deep, #multimodal #feature changes to #causal #differences. Result? Three conductances explained #phenotypic, #disease-related changes, an observation supported by subsequent #snRNA analysis.
#parallelcomputing #biophysical #simulations #multimodal #Feature #causal #differences #phenotypic #disease #snrna
We decided to focus our study on a single #celltype, dentate gyrus granule cells, and produce multiple #singlecell #data #modalities: #snRNA, #ephys, reconstructed morphologies and synaptic density.
#celltype #SingleCell #data #modalities #snrna #ephys