@bwyble @marcwhoward Oh, he has papers / theories on replay?? I thought it was mostly on #SplitterCells! I definitely want to know more

Woot-woot! Our review on #SplitterCells has been cited for the first time! Twice! 🥳​🍾​

Our review: Temporal context and latent state inference in the hippocampal splitter signal

Cited by:

• Kang & Toyoizumi, 2023
• Howard et al., 2023
  @marcwhoward thank you! ❤️​ Looking forward to reading your paper. We now have an eLife version (see above) that you could cite instead of the arXiv version, if you wanted!

Hi all 😃​
Our latest #Review on #SplitterCells is now published in @eLife !!
I will probably write a real thread on it when I get a chance... for now:

link: https://elifesciences.org/articles/82357

why: some neurons in the #Hippocampus (and other brain regions) of #Rats (and other mammals) have the fascinating ability to discriminate not just different presents, but different past or future states or trajectories in the same current situation. They could be related to #EpisodicMemory or #DecisionMaking 🤔​They are called 'trajectory-dependent cells' or Splitter Cells. 🔀​ We tried to make sense of them!

what: Hippocampal Splitter cells do a lot of puzzling stuff. For example there's a lot of them even in tasks that do not require the Hippocampus to be solved. They spread asymmetrically on a linear track leading to a choice point - 'past' splitters around the start and 'future' splitters towards the choice point. #TimeCells cells can be splitter cells (but they're usually #PlaceCells). Splitter cells evolve with experience, or maybe it is performance, nobody really knows. ​⁉️​ ... and a lot more weird stuff

conclusion: Two different computational models, the temporal context model and the latent state model, each explain a subset of the properties of splitter cells... so perhaps the Hippocampus implements both! But more experiments are needed to disentangle them 😄​

now what: questions or comments? Please let us know!! ✍️​

#Neuroscience #Cognition #NeuroPaper