#DendriticSpines contain a specialized ER, required for Ca2+ signaling, spine enlargement & #SynapticPlasticity. @yipinghsueh &co show that KLHL17 & SYNPO control the synaptic distribution of the ER, and so regulate synaptic plasticity #PLOSBiology https://plos.io/45PMrbR

A novel mechanism induced during attenuation of #ContextualFearMemory, involving Ser73 phosphorylation of #PSD95 in dCA1, suggests that PSD95-dependent #SynapticPlasticity in dCA1 is required for updating of such memories #PLOSBiology #neuroscience https://plos.io/3B4KScC

Upregulation of #connexin 30 in #astrocytes increases connectivity of #astroglial networks, but decreases synaptic transmission, altering #SynapticPlasticity & learning processes @EleonoreHardy_ @NathalieRouach @RancillacA &co #PLOSBiology https://plos.io/3UrHRMx

Upregulation of #connexin 30 in #astrocytes increases connectivity of #astroglial networks, but decreases synaptic transmission, altering #SynapticPlasticity & learning processes @EleonoreHardy_ @NathalieRouach @RancillacA &co #PLOSBiology https://plos.io/3UrHRMx