Intracellular NASPM blocks outward currents in GluA2-lacking AMPA receptors, with no relief at all from a large panel of auxiliary proteins. Important new tool for identifying AMPAR diversity at synapses. We need more ways to peel off the different types! Nice paper from Ian Coombs in the Cull-Candy-Farrant lab at UCL
https://elifesciences.org/articles/66765

#ionchannels #glutamate #synapses #synapticdiversity #electrophysiology