Putting together some slides on our efforts to detect tRNA modifications by #nanopore for RBI group meeting, and really enjoying this recent review from Esteban Orellana & colleagues at Boston Children's on #tRNAs in disease. Detecting and (eventually) quantifying these #modifications is a tough task, but the implications of being able to do so are huge. It's a fun challenge!
#nanopore #tRNAs #modifications