Check out our new paper in which we explored what happens when the boundaries between topologically associating chromatin domains ("TADs") get deleted - in this case in mice using CRISPR.

Spoiler alert: Some TAD boundaries are quite important!

https://www.nature.com/articles/s42003-023-04819-w

@LBNLBioSci @berkeleylab #TAD #TADBoundary #chromatin #knockout