How can #metabolic & #environmental cues modulate the #DNAdamage response? María Moriel-Carretero et al find master kinase #Tel1/ATM to bind #PI4P at the #Golgi, altering its availability in the nucleus and impacting kinetics, intensity and persistence of DNA DSB responses in yeast and human cells

#RefereedPreprint c/o @ReviewCommons

https://www.embopress.org/doi/10.15252/embj.2022112684