#ALT (not #telomerase) repairs damaged telomeres in #iPSCs… 😳 This finding comes in a sequences of others recognizing different
rules for #DNAdamage detection, #checkpoint activation and even #DNA repair in undifferentiated cells. 🧬👍
“Our findings suggest a previously unappreciated role for ALT in telomere maintenance in telomerase-positive iPSCs and reveal distinct iPSC-specific responses to targeted telomeric damage.” https://www.biorxiv.org/content/10.1101/2023.01.19.524780v1
#alt #telomerase #iPSCs #DNAdamage #checkpoint #dna
Just Published!
"Telomerase Reverse Transcriptase in Humans: From Biology to Cancer Immunity"
#cancer #cancerresearch #telomerase #immunology
Including comments from #telomerase researcher Miguel Godinho Ferreira at IRCAN Nice and @embojournal genome stability & dynamics editor @HVodermaier
Re-read the original article for free in our #anniversary collection:
https://www.embopress.org/page/journal/14602075/focus/40th-anniversary
Nice interview (in ES) with Spanish scientist Maria Blasco. #CNIO #telomerase #cancer #WomenSTEM #scicomm https://www.rtve.es/play/videos/encuentros-en-rtve/maria-blasco/6730817/
#cnio #telomerase #cancer #womenstem #scicomm
Why are germ cell tumors fairly rare? Lots of telomerase but nothing much happening besides preparing for the next generation :) #germline #DevBio #tumor #cancer #Telomerase
#germline #DevBio #tumor #cancer #telomerase