RT @eballestar@twitter.com

Happy to share our study showing #VitaminC boosting #immunogenicity properties of #DendriticCells through NF-κB- & #TET2 driven #DNAdemethylation ⁦@octaviompa@twitter.com⁩ ⁦@GerardGodoy3@twitter.com⁩ ⁦@JoseL_Sardina@twitter.com⁩ ⁦⁦@Eva_M_C@twitter.com⁩ ⁦@CarrerasIJC@twitter.com⁩ https://academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac941/6777795

🐦🔗: https://twitter.com/eballestar/status/1587739956100812800

One way that mutated immune cells might lead to an observed increase in #cardiovascular disease is through secretion of inflammatory #cytokines. In this recent abstract, the authors analyzed levels of 1,300 serum proteins for their association with #ClonalHematopoiesis mutations, finding that #TET2 mutations had several strong associations. Interesting to me that different CH mutations have different cytokine profiles, despite converging on increased #CVD risk: https://www.ahajournals.org/doi/abs/10.1161/circ.146.suppl_1.15719 #omics