Subset of neurons in #hypothalamus increases appetite & decreases #thermogenesis. @JongSohn &co show that ion channel GIRK2 functions in hypothalamic NPY/AgRP neurons to increase energy expenditure in mice and may control body weight @kaistpr #PLOSBiology https://plos.io/3qGa8Ev

@petersuber

Very interesting.
I have been wondering about the body temp drop since the study by Prostiv et al. came out in 2020 [1]
(& also wondering why not more attention has been given to it since it is kind of a big deal).

Futile cycling by Na/K ATPase contributes to thermogenesis [2] & Na/K ATPase activity is lower in autistic ppl. Will have to look up Lachnospiraceae & autism.

1- https://doi.org/10.7554/eLife.49555

2- https://rhyobrain.blogspot.com/2020/06/nak-atpase-thermogenesis-energetic-cost.html

#thermogenesis #microbiome #physiology

RT @Brunorm84@twitter.com

Mitochondrial RNA stimulates beige adipocyte development in young mice #thermogenesis #obesity @NatMetabolism@twitter.com https://www.nature.com/articles/s42255-022-00683-w

🐦🔗: https://twitter.com/Brunorm84/status/1597294322546012160

RT @kazaklab
Excited to share our new work published in @NatMetabolism led by an all-star fellow in the lab @jananerahbani where we discover that #thermogenesis by the futile creatine cycle is regulated through alpha-adrenergic receptor signaling.
https://www.nature.com/articles/s42255-022-00667-w
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