Defenestrate has two meanings:

1. to throw (a person or thing) out of a window.

2. to suddenly remove (a person) from an important position or office.

Both meanings come from the same incident the word was coined to describe: The "Defenestration of Prague," May 21st 1618, two Catholic deputies to the Bohemian national assembly and a secretary were tossed out the window of the castle of Hradschin.

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