How to avoid getting infected with the brain parasite, Toxoplasma g. 🙀

(I didn’t know you can get it from eating undercooked pork/poultry 😱 #goVegan )

#NutritionFacts #parasites #toxoplasma

https://nutritionfacts.org/video/how-to-prevent-toxoplasmosis/

https://www.science.org/content/article/reality-check-can-cat-poop-cause-mental-illness
Oh just a random #science article that seemed interesting about #Toxoplasma gondii, a brain parasite for absolutely no particular reason🤷🏻‍♀️

Was reading about Yuri Knorozov a Soviet linguist who deciphered the Mayan script in 1953 who claimed that his cat Biscuits communicated with him telepathically. I’d have definitely been friends with him🖤🖤

#CRISPR screen identifies secreted proteins that help #Toxoplasma overcome human cell immune defenses; these differ from those needed to infect mouse cells, so the #parasite's wide host range may depend on its large secretome @Moritz_Treeck #PLOSBiology https://plos.io/3K34ClR

'Finally, and most recently, we have become interested in understanding the interactions of Toxoplasma with mucus. When you ingest Toxoplasma, it has to get through the #microbiota, cross the mucous layer, get to the epithelium, cross the epithelium, find its way into the blood, and then into the brain and skeletal muscles. But I never really paused and thought about the impact of mucus on that initial infection until I taught #immunology. And so, now I'm interested in looking at the interaction of #Toxoplasma with goblet cells.'

https://journals.biologists.com/jcs/article/136/11/jcs261304/312614/Cell-scientist-to-watch-Pascale-Guiton

Both maternal #IFNγ exposure and acute prenatal infection with #Toxoplasma gondii activate fetal #hematopoietic #stemcells
Anna E Beaudin and colleagues
https://www.embopress.org/doi/full/10.15252/embj.2022112693

Referenced link: https://phys.org/news/2023-06-genetic-screen-clues-toxoplasma-host.html
Discuss on https://discu.eu/q/https://phys.org/news/2023-06-genetic-screen-clues-toxoplasma-host.html

Originally posted by Phys.org / @physorg_com: http://nitter.platypush.tech/physorg_com/status/1666074733387849730#m

Novel genetic screen provides clues on how #Toxoplasma behaves within a #host @osaka_univ @CellReports https://linkinghub.elsevier.com/retrieve/pii/S2211124723006034 https://phys.org/news/2023-06-genetic-screen-clues-toxoplasma-host.html

"Our investigation reveals that the fetal HSCs respond to T. gondii infection with virulence-dependent changes in proliferation, self-renewal potential, and lineage output. Furthermore, maternal IFNγ crosses the fetal–maternal interface, where it is perceived by fetal HSCs."

#Immunology #Interferon #Toxoplasma

https://www.embopress.org/doi/full/10.15252/embj.2022112693

Study shows that a small-molecule inhibitor of #Toxoplasma #myosin A reduces #parasite motility & alters disease progression in vivo, suggesting a new approach to treating infections by #apicomplexan parasites #PLOSBiology https://plos.io/42ySrUG

We’ve just published our 25th #ReviewedPreprint!

Editors and reviewers praised this #preprint on calcium signalling in #Toxoplasma gondii as “important” and “convincing” 💡 https://elifesciences.org/reviewed-preprints/85654/reviews?utm_source=mastodon&utm_medium=social&utm_campaign=organic

Check out more #ReviewedPreprints here: https://elifesciences.org/reviewed-preprints?utm_source=mastodon&utm_medium=social&utm_campaign=organic

"Here, we investigated the fetal hematopoietic response to maternal infection with Toxoplasma gondii (T. gondii), an intracellular parasite that elicits Type II IFNγ-mediated maternal immunity."

#immunology #Parasitology #Toxoplasma #HostPathogen #InfetionImmunity #Preprint

https://www.biorxiv.org/content/10.1101/2022.11.29.518417v3

Lab manager in parasitology (Plasmodium and Toxoplasma) @JimahLab

Lab Manager/Technician/Scientist in Parasitology in the Jimah Lab at Princeton University

https://jobrxiv.org/job/jimah-lab-department-of-molecular-biology-princeton-university-27778-lab-manager-in-parasitology-plasmodium-and-toxoplasma/?feed_id=37057

#ScienceJobs #job #malaria, #toxoplasma, #parasites, #plasmodium
...
https://jobrxiv.org/job/jimah-lab-department-of-molecular-biology-princeton-university-27778-lab-manager-in-parasitology-plasmodium-and-toxoplasma/?feed_id=37057

Lab manager in parasitology (Plasmodium and Toxoplasma) @JimahLab

Lab Manager/Technician/Scientist in Parasitology in the Jimah Lab at Princeton University

https://jobrxiv.org/job/jimah-lab-department-of-molecular-biology-princeton-university-27778-lab-manager-in-parasitology-plasmodium-and-toxoplasma/?feed_id=35198

#ScienceJobs #job #malaria, #toxoplasma, #parasites, #plasmodium
...
https://jobrxiv.org/job/jimah-lab-department-of-molecular-biology-princeton-university-27778-lab-manager-in-parasitology-plasmodium-and-toxoplasma/?feed_id=35198

RT alexwaichan: ~1 in 4 people 🌎 have been infected with this pathogen ☣️. Here is a video of it destroying its host cell as it escapes to find a new target. It's not viral, bacterial, or fungal.

Check out this 🧵 to see what we discovered in #Toxoplasma #Calcium #VesicularTrafficking 🎣 1/12

#Parasite common in #cats causes #abortion in bighorn #sheep.

#conservation #Toxoplasma

https://phys.org/news/2023-01-parasite-common-cats-abortion-bighorn.html

@Volksverpetzer
Jetzt wäre noch interessant, ob es einen Zusammenhang zwischen #Impfgegnerschaft und einer vorangegangenen #Toxoplasmose Infektion gibt?
Jaroslav #Flegr (#Karls-Universität #Prag) hat bereits vor Jahren festgestellt, dass insbesondere Männer, die sich mit #Toxoplasma gondii #infiziert hatten, #risikobereiter und häufiger in #Autounfälle verwickelt als Menschen ohne.
#Risiko

Toxo invasion. @MirkoSinger @MeissnerLab &co identify a protein complex containing a CRMPA/CRMPB heterodimer with multiple transmembrane domains as being essential for host cell invasion by the #apicomplexan #parasite #Toxoplasma gondii #PLOSBiology https://plos.io/3vJePMM

Toxo invasion. @MirkoSinger @MeissnerLab &co identify a protein complex containing a CRMPA/CRMPB heterodimer with multiple transmembrane domains as being essential for host cell invasion by the #apicomplexan #parasite #Toxoplasma gondii #PLOSBiology https://plos.io/3vJePMM

Since there is lot of #caturday #cats #cat #catsofmastodon toots. I wonder how many people did heard about #toxoplasma ability to change your behaviour? #science #parasite https://www.youtube.com/watch?v=rqno7K2zXi4&t=219s

Your daily reminder of who is really in charge around here... 😺💸

"Students (n = 1495) who tested IgG positive for Toxoplasma Gondii exposure were 1.4× more likely to major in business and 1.7× more likely to have an emphasis in ‘management and entrepreneurship' over other business-related emphases."

https://doi.org/10.1098/rspb.2018.0822

#Toxoplasma #Gondii #ToxoplasmaGondii #BrainWorms #Caturday

The article by Olivereira Souza et al. showing that IMC10 and LMF1 mediate mitochondrial morphology through mitochondrion–pellicle contact sites in Toxoplasma gondii is #openaccess: https://journals.biologists.com/jcs/article/135/22/jcs260083/282114/IMC10-and-LMF1-mediate-mitochondrial-morphology
#cellbiology #research #toxoplasma #mitochondria #opendata #openscience