CellBioNews · @cellbionews
113 followers · 1845 posts · Server scientificnetwork.de

Loic Binan of the Broad:
All-optical genetic screens of intracellular and intercellular circuits with Perturb-FISH

Various CRISPR-based methods to look (multiplexed) at outcomes after knockdown to explore gene expression circuits, those are great, but want richer data (morphology etc)

one guide per cell (knock down one gene per cell) see via MERFISH, then identify the perturbed gene via in situ T7 transcription (same chemistry as MERFISH)

1/2

#cssinglecells23 #transcriptome #transcriptional

Last updated 1 year ago

Haojia Wu · @haojiawu
165 followers · 69 posts · Server mastodon.haojia-wu.com

GAGE-seq for 3D genome and transcriptome co-profiling within the same single cell
biorxiv.org/content/10.1101/20

#singlecell #transcriptome #genomics

Last updated 1 year ago

CellBioNews · @cellbionews
72 followers · 1578 posts · Server scientificnetwork.de
CellBioNews · @cellbionews
58 followers · 1423 posts · Server scientificnetwork.de
CellBioNews · @cellbionews
54 followers · 1319 posts · Server scientificnetwork.de
spiewak2011 · @spiewak2011
0 followers · 42 posts · Server mstdn.social

Predicting Which Bladder Cancer Patients Will Respond to Immunotherapy

youtube.com/watch?v=cSlw_rtxvY

#transcriptome #bioinformatics #urology

Last updated 1 year ago

spiewak2011 · @spiewak2011
0 followers · 37 posts · Server mstdn.social

Association of 18-Gene expression profile (GEP) with clinical outcomes in patients with metastatic triple-negative breast cancer (mTNBC) treated with pembrolizumab (Pembro) or chemotherapy (Chemo) in KEYNOTE-119

esmoopen.com/article/S2059-702

#transcriptome #geneexpressionprofiling

Last updated 1 year ago

CellBioNews · @cellbionews
54 followers · 1252 posts · Server scientificnetwork.de
CellBioNews · @cellbionews
54 followers · 1239 posts · Server scientificnetwork.de
Federico Comitani · @inatimoc
48 followers · 23 posts · Server fediscience.org

Shamless plug warning! โš ๏ธ

Our last paper on heterogeneity of is out.
Did you think a quiet translates into a quiet ? Think again!

on a pan-cancer cohort revealed new diagnostic subtypes and helped us train a model to identify tumour components in samples.

Read it here, it's : nature.com/articles/s41591-023


#ml #machinelearning #Transcriptomics #precisionmedicine #openaccess #oncology #clinical #cnn #rnaseq #clustering #multiscale #transcriptome #genome #cancer #pediatric #transcriptional

Last updated 2 years ago

CellBioNews · @cellbionews
36 followers · 803 posts · Server scientificnetwork.de
CellBioNews · @cellbionews
36 followers · 787 posts · Server scientificnetwork.de

๐Ÿ“ข Don't miss: Tuuli Lappalainen @tuuliel_lab (@nygenome @KTHuniversity @scilifelab) will speak at our !

๐Ÿ“œ Functional variation in the human : lessons from the
๐Ÿ“† 27. FEB, 11:00 AM (CET)
๐Ÿ“ @MPI_MolGen,
๐Ÿ”— molgen.mpg.de/events/33625/396

#dahlemcolloquium #genome #transcriptome #berlin

Last updated 2 years ago

Didier AURELLE · @didier_aurelle
112 followers · 50 posts · Server ecoevo.social

New article on the strucutre : with and data we study the Atlantic/Mediterranean divergence, and a cryptic lineage in the Atlantic. More information here: onlinelibrary.wiley.com/doi/fu

#genetic #paramuricea #octocorals #microsatellites #transcriptome

Last updated 2 years ago

CellBioNews · @cellbionews
24 followers · 410 posts · Server scientificnetwork.de
CellBioNews · @cellbionews
21 followers · 370 posts · Server scientificnetwork.de
darachm · @darachm
139 followers · 276 posts · Server genomic.social

Oh now this is fun
Nielsen etc did absolute-calibrated and on yeast in chemostats (C-limited), so another dope data set for the Theory of

Also estimating the % occupancy of individual , that 35 or so are >90% used up for throughput, so maybe limiting metabolic chokepoints

Oh and tldr -acids are super limiting so

nature.com/articles/s41467-022

#proteome #transcriptome #metabalome #piechart #microbialgrowth #enzyme #amino #aminoacidmetabolismrules

Last updated 2 years ago

Chuixiang (Tree) Yi · @TreeYi
10 followers · 1757 posts · Server mastodon.world

RT @AbioticStress
Article by @HimabinduKudapa @RutwikBarmukh @GargVanika @Anuchitikineni @rajvarshney @IJMS_MDPI

Comprehensive Profiling Uncovers Molecular Mechanisms & Potential Candidate Associated with Response in

mdpi.com/1422-0067/24/2/1369#

#transcriptome #genes #HeatStress #chickpea #plantsci

Last updated 2 years ago