https://youtu.be/iRlrA-B7lOU

"A mechanical stimulus to skeletal muscle activates the sympathetic nervous system during exercise. ... Our data suggests that TRPV4 plays an important role in mechanotransduction contributing to the cardiovascular responses during exercise. "

#physiology #TRPV4 #TRPchannels

news article:
https://www.sciencealert.com/ultrasound-induces-torpor-like-state-in-animals-experiment-shows

"the ultrasound was activating the TRPM2 ion channel in neurons of the hypothalamus preoptic area, demonstrating this is an ultrasound-sensitive ion channel that plays a role in sending animals into
ultrasound-induced hypothermia & hypometabolism]"

#metabolism #torpor #TRPchannels #SpaceMedicine #Brain

Have my MPhil viva next Monday in deepest darkest Cambridge! Reading up on TRP channels, naked mole-rats, cloning and apoptosis. Here is a beautiful review on the role of TRP channels in pain.

https://www.nature.com/articles/s41583-022-00611-7

#TRPchannels #Biophysics #electrophysiology #ionchannels