Started taking #TUDCA, because #UDCA was recently shown to prevent viral binding of #covid to #ace2 receptors... And I really like it... Except that it gives me reflux a little bit (which is fairly easily countered with an antacid).

Looks hopeful, and impressive - a treatment to prevent COVID targeting a receptor, rather than the specific variant of the virus. https://www.cam.ac.uk/stories/UDCA-COVID19 #COVID #UDCA

12/5/22 Nature: FXR inhibition may protect from #SARSCoV2 infection by reducing ACE2 https://buff.ly/3UxyUzA

Ursodeoxycholic acid (#UDCA) , an FXR blocker, is a generic drug used for liver disease. It downregulates ACE2.

UDCA (aka Ursodiol or Actigall) has been used for cholestasis of pregnancy.

This study used UDCA in organoids, mouse/hamster models and in people and shows that UDCA may block or reduce the severity of #COVID infections.

#COVID19