Plot: Changing identities, causing chaos.
@Jamesdw pulls a 'Bond' move turning patient derived cells to organoids to unravel renal dysfunction in #BardetBiedlSyndrome
Watt lab

#UKCilia2023 #UKCiliaNetwork @Mill_lab #BSCB @J_Cell_Sci #GenSocUK

Jacqueline Oberlin likes all things straight! Teases fishy genes behind #JoubertSyndrome at Bachmann-Gagescu Lab.
A talk can be cute only at #UKCilia2023 :)

#UKCiliaNetwork @Mill_lab #BSCB @J_Cell_Sci #GenSocUK

Skip and jump with Melanie Eschment
in 2D and 3D for #JoubertSyndrome!
#Ciliopathies are difficult, behind-the-scenes stories are essential.
A Bachmann-Gagescu Lab production.

#UKCilia2023 #UKCiliaNetwork @Mill_lab #BSCB @J_Cell_Sci #GenSocUK

The origins of cilia: donuts!
CLEM-STEM magic by Kerstin Schmidt will leave you wanting more! 🍩
Witzgall lab
#cilia #UKCilia2023 #UKCiliaNetwork @Mill_lab #BSCB @J_Cell_Sci #GenSocUK

Funny eyes of FayGNewton
's mice!
Connecting cilium📢 :
#RetinitisPigmentosa, take your pick of mechanisms for retinal degeneration
Photoreceptors, please comply!

#UKCilia2023 #UKCiliaNetwork @Mill_lab #BSCB
@J_Cell_Sci #GenSocUK

Great discussion, great questions- thanks to all my speakers & our audience! Todays session was poster prize winners from EMBO Cilia 2022- more surprises next time! We will be back 🗓️APRIL 18th 2023 🗓️ for our second session #ukcilia2023- sign up here if you are not on my list! Free and open to all: https://eventbrite.co.uk/e/bscb-gensoc-uk-cilia-network-e-symposia-series-tickets-122092125835 /fin

How #photoreceptors die in #retinitispigmentosa using #scRNAseq, proteomics & quantitative imaging with slow #RPGR & fast #PDE6B mouse models- understanding early and late disease mechanisms! Great talk by Fay Newton, postdoc extraordinaire funded by Fight for Sight UK in Megaw/Mill labs at MRC HGU, University of Edinburgh. #ukcilia2023 /7

Understanding #Bardet-Biedl renal phenotypes- human kidney disease in a dish for #ciliopathies- HipSci human healthy donors and rare disease, including 50 BBS patients- ambitious work from James Williams a PhD candidate
funded by BBS UK Charity in FIona Watt's lab at KCL! #ukcilia2023 /6

Everyone’s favorite membrane-less organelles #Centriolarsatellites in #centrosome remodelling and #ciliogenesis- a paralogue in Drosophila opens the field to other model organisms. Great talk from Claudia Pachinger from the Dammermann Lab @ MaxvPerutzvLabs! #ukcilia2023 /5

A Bachmann lab double header, next up was a phenomenal Masters project on unpicking molecular cascades underlying body-axis straightening in zebrafish, #ciliopathies & #scoliosis from Jacqueline Oberlin from Bachmann-Gagescu lab University of Zurich! #ukcilia2023 /4

Next up, modelling Joubert Syndrome in a dish- understanding poor genoptype-phenotype correlations in cerebral organoids for #ciliopathies! We marvelled at Melanie Eschment, Bachmann-Gagescu lab University of Zurich who dazzles us with neural phenotypes which differ in 2 and 3D! #ukcilia2023 /3

It was a great session! We kick off with a masterclass in the first steps of #cilia membrane formation by Kerstin Schmidt from the Witzgall lab University of Regensburg, DE combining CLEM & STEM tomography for partial donuts in early ciliogenesis! #ukcilia2023 /2

We had an amazing 42nd BSCB GenSoc UK Cilia Network e-symposium online today- back after a 7 month hiatus with 241-strong audience! However how do I hype the amazing #ECRs- students and postdocs- to a field that has not yet migrated here... We do this to 'grow' their networks but means me putting original content on :twitter: Dilemmas.... #UKCilia2023 /1

We had an amazing 42nd BSCB GenSoc UK Cilia Network e-symposium online today- back after a 7 month hiatus with 241-strong audience! However how do I hype the amazing #ECRs- students and postdocs- to a field that has not yet migrated here... We do this to 'grow' their networks but means me putting original content on :twitter: Dilemmas.... #UKCilia2023 /1

@cilia

Followed by fantastic work on Cep290 mutant neurons in organoid cultures ... Great talk of Melanie Eschment, PhD candidate from Ruxandra's lab in Zurich.

Now her colleague Jacqueline Oberlin continues on skeletal development in zebrafish ...

I stop posting here and keep on enjoying the fantastic talks 🙂

#UKCilia2023 #Joubert #CIlia

#UKCilia2023

Great start with Kerstin Schmidt presenting fantastic pictures of the very earliest steps in ciliogenesis based on EM tomography.

At the very end a picture similar to this: :dom:

😉

@cilia #cilia #ciliopathies