#IDMastodon #Epigenetics & clinical observations referring to Betacoronavirus lead to the conjecture that #SARSCoV2 🦠 may have the ability to infect #Lymphocytes using a different way than the spike protein. In addition to inducing the death of lymphocytes, thus drastically reducing their population & causing a serious #immunedeficiency allows it to remain hidden for long periods of latency using them as a #viralreservoir in #LongCovid

@kroltanz imo, the simplest explanation as to why monocytes continue to be switched on is that they continue to encounter pathogens 😬

#ViralPersistence #ViralReservoir

"Our recovery of nef proviral sequences from the lungs of all participants, albeit in limited numbers in some cases (in particular, participants 3, 5 and 7), confirms this organ as a site of long-term HIV persistence during ART."

#HIV #ViralReservoir #art

https://journals.plos.org/plospathogens/article?id=10.1371/journal.ppat.1010613#sec006

More on #covid and #clots. I think this is the heart of most #postCOVID issues, along with #immuneimpairment and #viralreservoir.

https://www.forbes.com/sites/williamhaseltine/2022/03/04/antibody-activated-endothelial-cells-increase-the-risk-of-blood-clots-with-covid-19/