Oncolytic DNX-2401 virotherapy plus pembrolizumab in recurrent glioblastoma: a phase 1/2 trial #cancer #brain #viraltherapy #intratumoral

"Oncolytic viruses are capable of reconditioning the tumor microenvironment toward a ‘hot’ phenotype, providing rationale for combinatorial therapy with checkpoint inhibitors"

https://www.nature.com/articles/s41591-023-02347-y