A DFT study on the probability of using the heteroatom decorated graphitic carbonitride (g-C<sub>3</sub>N<sub>4</sub>) species for delivering of three novel Multiple sclerosis drugs

https://gregory-ms.com/articles/43205/

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<em>Limosilactobacillus reuteri</em> in immunomodulation: molecular mechanisms and potential applications

https://gregory-ms.com/articles/34176/

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S1PR-1/5 modulator RP-101074 shows beneficial effects in a model of central nervous system degeneration

https://gregory-ms.com/articles/34177/

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The protective effects of sesamol and/or the probiotic, <em>Lactobacillus rhamnosus</em>, against aluminum chloride-induced neurotoxicity and hepatotoxicity in rats: Modulation of Wnt/β-catenin/GSK-3β, JAK-2/STAT-3, PPAR-γ, inflammatory, and apoptotic pathways

https://gregory-ms.com/articles/24730/

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Brilliant. #pencils @andy https://www.si.com/extra-mustard/2023/08/21/phillies-bryson-stotts-no-2-pencil-bat

The novel small molecule TPN10518 alleviates EAE pathogenesis by inhibiting AP1 to depress Th1/Th17 cell differentiation

https://pubmed.ncbi.nlm.nih.gov/37591119/?fc=20210216052009&ff=20230818004212&v=2.17.9.post6+86293ac

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Multicenter, randomized, double-blind, parallel-group extension to study AC 058B201 to investigate the long-term safety, tolerability, and efficacy of 10, 20, and 40 mg/day ponesimod, an oral S1P1 ...

https://www.clinicaltrialsregister.eu/ctr-search/search?query=eudract_number%3A2009-011470-15

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<em>Mycobacterium avium</em> subsp. <em>paratuberculosis</em> Antigens Elicit a Strong IgG4 Response in Patients with Multiple Sclerosis and Exacerbate Experimental Autoimmune Encephalomyelitis

https://pubmed.ncbi.nlm.nih.gov/37511812/?fc=20210216052009&ff=20230729121032&v=2.17.9.post6+86293ac

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Intravenous transplantation of bone marrow-derived mesenchymal stromal cells in patients with multiple sclerosis, a phase I/IIa, double blind, randomized controlled study

https://pubmed.ncbi.nlm.nih.gov/37515913/?fc=20210216052009&ff=20230730012033&v=2.17.9.post6+86293ac

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The small molecule Erk1/2 signaling pathway inhibitor PD98059 improves DNA repair in an experimental autoimmune encephalomyelitis SJL/J mouse model of multiple sclerosis

https://pubmed.ncbi.nlm.nih.gov/37491119/?fc=20210216052009&ff=20230726014032&v=2.17.9.post6+86293ac

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Ketogenic diet attenuates neuroinflammation and induces conversion of M1 microglia to M2 in an EAE model of multiple sclerosis by regulating the NF-κB/NLRP3 pathway and inhibiting HDAC3 and P2X7R activation

https://pubmed.ncbi.nlm.nih.gov/37466915/?fc=20210216052009&ff=20230719133032&v=2.17.9.post6+86293ac

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RNF157 attenuates CD4<sup>+</sup> T cell-mediated autoimmune response by promoting HDAC1 ubiquitination and degradation

https://pubmed.ncbi.nlm.nih.gov/37441600/?fc=20210216052009&ff=20230713193015&v=2.17.9.post6+86293ac

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Green tea EGCG inhibits naïve CD4<sup>+</sup> T cell division and progression in mice: An integration of network pharmacology, molecular docking and experimental validation

https://pubmed.ncbi.nlm.nih.gov/37441168/?fc=20210216052009&ff=20230713193015&v=2.17.9.post6+86293ac

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Oral administration of procyanidin B2 3,3"-di-O-gallate ameliorates experimental autoimmune encephalomyelitis through immunosuppressive effects on CD4<sup>+</sup> T cells by regulating glycolysis

https://pubmed.ncbi.nlm.nih.gov/37406847/?fc=20210216052009&ff=20230706012111&v=2.17.9.post6+86293ac

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Total Flavonoids of Astragalus Inhibit Activated CD4[Formula: see text] T Cells and Regulate Differentiation of Th17/Th1/Treg Cells in Experimental Autoimmune Encephalomyelitis Mice by JAK/STAT and NF[Formula: see text]B Signaling Pathways

https://pubmed.ncbi.nlm.nih.gov/37385966/?fc=20210216052009&ff=20230630013113&v=2.17.9.post6+86293ac

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DAPTA, a C-C Chemokine Receptor 5 (CCR5), Leads to the Downregulation of Notch/NF-κB Signaling and Proinflammatory Mediators in CD40<sup>+</sup> Cells in Experimental Autoimmune Encephalomyelitis Model in SJL/J Mice

https://pubmed.ncbi.nlm.nih.gov/37371605/?fc=20210216052009&ff=20230628070016&v=2.17.9.post6+86293ac

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JAK2/STAT5 inhibition protects mice from experimental autoimmune encephalomyelitis by modulating T cell polarization

https://pubmed.ncbi.nlm.nih.gov/37269741/?fc=20210216052009&ff=20230604014013&v=2.17.9.post6+86293ac

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AXL-Induced Autophagy mitigates experimental autoimmune encephalomyelitis by suppressing microglial inflammation via the PI3K/AKT/mTOR signaling pathway

https://pubmed.ncbi.nlm.nih.gov/37263067/?fc=20210216052009&ff=20230602014015&v=2.17.9.post6+86293ac

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Dental pulp stem cell-derived exosomes revitalize salivary gland epithelial cell function in NOD mice via the GPER-mediated cAMP/PKA/CREB signaling pathway

https://translational-medicine.biomedcentral.com/articles/10.1186/s12967-023-04198-0

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Distcc: A fast, free distributed C/C++ compiler
https://www.distcc.org/
posted by #technewsbot #technews